Caspase expression in oral squamous cell carcinoma

Background Apoptosis is a genetically programmed form of cell death, of which caspases are the central components. Methods By tissue microarray of 229 cases of oral squamous cell carcinoma (OSCC), we analyzed the immunoexpression of caspases 3, 6, 7, 8, 9, and 10. Results All proteins that we examin...

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Veröffentlicht in:	Head & neck 2011-08, Vol.33 (8), p.1191-1198
Hauptverfasser:	Coutinho-Camillo, Cláudia Malheiros, Lourenço, Silvia Vanessa, Nishimoto, Ines Nobuko, Kowalski, Luiz Paulo, Soares, Fernando Augusto
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged apoptosis Biological and medical sciences Biomarkers, Tumor - analysis Biopsy, Needle Carcinoma, Squamous Cell - enzymology Carcinoma, Squamous Cell - genetics Carcinoma, Squamous Cell - mortality Carcinoma, Squamous Cell - pathology Case-Control Studies caspases Caspases - genetics Caspases - metabolism Disease Progression Disease-Free Survival Female Gene Expression Regulation, Neoplastic Humans Immunohistochemistry Kaplan-Meier Estimate Male Medical sciences Microarray Analysis - methods Middle Aged Mouth Neoplasms - enzymology Mouth Neoplasms - genetics Mouth Neoplasms - mortality Mouth Neoplasms - pathology Neoplasm Staging oral squamous cell carcinoma Otorhinolaryngology. Stomatology Predictive Value of Tests Prognosis Proportional Hazards Models Reference Values Survival Analysis Tissue Embedding tissue microarray Tumors Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology
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