Participation of glucocorticoid receptors in morphine tolerance development through the signal pathway of extracellular signal-regulated kinase

To investigate the mechanism of glucocorticoid receptors (GR) participating in morphine tolerance development via the extracellular signal-regulated kinase (ERK) signal pathway. Forty healthy male SD rats were implanted with intrathecal catheters and then randomized into 4 groups: Group C received a...

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Veröffentlicht in:	Zhong hua yi xue za zhi 2011-05, Vol.91 (18), p.1272-1275
Hauptverfasser:	Chen, Yi, Yu, Yong-Hao, Zhai, Mei-Li, Wang, Zhuang, Wang, Guo-Lin
Format:	Artikel
Sprache:	chi
Schlagworte:	Animals Drug Tolerance Extracellular Signal-Regulated MAP Kinases - metabolism Male Morphine - metabolism Morphine - pharmacology Rats Rats, Sprague-Dawley Receptors, Glucocorticoid - metabolism Signal Transduction
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