Asymmetric Mannich Reaction of Imines Derived from Aliphatic and Aromatic Aldehydes Catalyzed by Diarylprolinol Silyl Ether

Anti Mannich, try this! A direct asymmetric Mannich reaction catalyzed by a diarylprolinol silyl ether was developed to afford the anti‐Mannich product with excellent enantioselectivity. Imines derived from both aliphatic and aromatic aldehydes were successfully used to obtain the synthetically impo...

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Veröffentlicht in:	Chemistry : a European journal 2011-07, Vol.17 (30), p.8273-8276
Hauptverfasser:	Urushima, Tatsuya, Ishikawa, Hayato, Hayashi, Yujiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldehydes Aliphatic compounds asymmetric synthesis Asymmetry Chemical reactions Chemistry domino reactions enantioselectivity Ethers Imines Mannich reaction organocatalysis
Online-Zugang:	Volltext
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