Maternal and fetal leptin and ghrelin levels: relationship with fetal growth

Purpose In our study, we investigated the influence of plasma levels ghrelin, leptin and other metabolic hormones (ILGF-1 and ILGF-2) in pregnants in regulating fetal body weight and mode of delivery. Methods A total of 36 appropriately healthy pregnants 19–36-year-old were involved in the study. De...

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Veröffentlicht in:	Archives of gynecology and obstetrics 2011-08, Vol.284 (2), p.327-329
Hauptverfasser:	Saylan, Filiz, Köken, Gülengül, Cosar, Emine, Köken, Tülay, Saylan, Arif, Arıöz, Dağıstan Tolga, Şahin, Figen, Köken, Reşit, Yılmazer, Mehmet
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Birth Weight Body Mass Index Endocrinology Female Fetal Blood - metabolism Fetal Development - physiology Ghrelin - blood Gynecology Human Genetics Humans Insulin-Like Growth Factor I - metabolism Insulin-Like Growth Factor II - metabolism Leptin - blood Materno-Fetal Medicine Medicine Medicine & Public Health Metabolism Obstetrics/Perinatology/Midwifery Parturition - blood Pregnancy - blood Pregnancy Trimesters - blood Young Adult
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Zusammenfassung:	Purpose In our study, we investigated the influence of plasma levels ghrelin, leptin and other metabolic hormones (ILGF-1 and ILGF-2) in pregnants in regulating fetal body weight and mode of delivery. Methods A total of 36 appropriately healthy pregnants 19–36-year-old were involved in the study. Demographic chracteristics, serum ghrelin, leptin, IGF-1 and IGF-2 levels of the pregnants were studied. Results Plasma ghrelin and leptin levels did not differ significantly among trimesters and delivery, in contrast to IGF-I and IGF-II concentrations were significantly higher in the first half of the pregnancy ( P
ISSN:	0932-0067 1432-0711
DOI:	10.1007/s00404-010-1651-6