Cholinesterase inhibitor blockade and its prevention by statins of sympathetic alpha 7-nAChR-mediated cerebral nitrergic neurogenic vasodilation

Cholinesterase inhibitors (ChEIs) have been used to treat Alzheimer's disease (AD). The efficacy of these drugs, however, is less than satisfactory. The possibility that ChEIs may have effects unrelated to ChE activity, such as negatively modulate neuronal nicotinic acetylcholine receptors (nAC...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2006-12, Vol.26 (12), p.1562-1576
Hauptverfasser:	Mozayan, Mansoor, Chen, Mei-Fang, Si, Minliang, Yi Chen, Po, Premkumar, Louis S, Lee, Tony J F
Format:	Artikel
Sprache:	eng
Schlagworte:	Xenopus
Online-Zugang:	Volltext
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