Apoptotic and Antiapoptotic Mechanisms After Traumatic Brain Injury

Caspase and inhibitor of apoptosis (IAP) expression was examined in rats subjected to moderate traumatic brain injury (TBI) using a parasagittal fluid-percussion brain insult (1.7 to 2.2 atm). Within 1 hour after injury, caspase-8 and −9, two initiators of apoptosis, were predominantly expressed in...

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Veröffentlicht in:	Journal of cerebral blood flow and metabolism 2001-10, Vol.21 (10), p.1189-1198
Hauptverfasser:	Keane, Robert W., Kraydieh, Susan, Lotocki, George, Alonso, Ofelia F., Aldana, Phillip, Dietrich, W. Dalton
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Bacterial Proteins - metabolism Biological and medical sciences Brain Injuries - enzymology Brain Injuries - pathology Caspase 3 Caspase 8 Caspase 9 Caspases - metabolism Cerebral Cortex - enzymology Cerebral Cortex - pathology Hippocampus - enzymology Hippocampus - pathology Immunohistochemistry Inhibitor of Apoptosis Proteins Injuries of the nervous system and the skull. Diseases due to physical agents Insect Proteins Kinetics Male Medical sciences Proteins Rats Rats, Sprague-Dawley Traumas. Diseases due to physical agents
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