Effects of Moderate Hypothermia on IL-1β–Induced Leukocyte Rolling and Adhesion in Pial Microcirculation of Mice and on Proinflammatory Gene Expression in Human Cerebral Endothelial Cells

Although the neuroprotective effects of hypothermia have been known for a long time, the molecular correlates of this neuroprotection are poorly understood. In this study, the authors investigated how hypothermia affects inflammatory responses in the brain elicited by systemic injection of IL-1β. Le...

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Veröffentlicht in:Journal of cerebral blood flow and metabolism 2001-11, Vol.21 (11), p.1310-1319
Hauptverfasser: Sutcliffe, Ian T., Smith, Holly A., Stanimirovic, Danica, Hutchison, James S.
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Sprache:eng
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