Fractionated stereotactic reirradiation and concurrent temozolomide in patients with recurrent glioblastoma

The aim of this paper is to evaluate the efficacy of fractionated stereotactic radiotherapy (FSRT) and concomitant temozolomide (TMZ) as a salvage treatment option in patients with recurrent glioblastoma (GBM). Between May 2006 and December 2009, 36 patients with recurrent GBM received FSRT plus con...

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Veröffentlicht in:	Journal of neuro-oncology 2011-07, Vol.103 (3), p.683-691
Hauptverfasser:	Minniti, G., Armosini, V., Salvati, M., Lanzetta, G., Caporello, P., Mei, M., Osti, M. F., Maurizi, R. Enrici
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Antineoplastic Agents, Alkylating - therapeutic use Brain Neoplasms - drug therapy Brain Neoplasms - mortality Brain Neoplasms - radiotherapy Clinical Study – Patient Study Combined Modality Therapy Dacarbazine - analogs & derivatives Dacarbazine - therapeutic use Disease-Free Survival DNA Modification Methylases - metabolism DNA Repair Enzymes - metabolism Female Glioblastoma - drug therapy Glioblastoma - mortality Glioblastoma - radiotherapy Humans Karnofsky Performance Status Magnetic Resonance Imaging Male Medicine Medicine & Public Health Middle Aged Neoplasm Recurrence, Local - drug therapy Neoplasm Recurrence, Local - mortality Neoplasm Recurrence, Local - radiotherapy Neurology Oncology Retrospective Studies Stereotaxic Techniques Treatment Outcome Tumor Suppressor Proteins - metabolism
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