VEGF-expressing human umbilical cord mesenchymal stem cells, an improved therapy strategy for Parkinson's disease

The umbilical cord provides a rich source of primitive mesenchymal stem cells (human umbilical cord mesenchymal stem cells (HUMSCs)), which have the potential for transplantation-based treatments of Parkinson's Disease (PD). Our pervious study indicated that adenovirus-associated virus-mediated...

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Veröffentlicht in:	Gene therapy 2011-04, Vol.18 (4), p.394-402
Hauptverfasser:	Xiong, N, Zhang, Z, Huang, J, Chen, C, Jia, M, Xiong, J, Liu, X, Wang, F, Cao, X, Liang, Z, Sun, S, Lin, Z, Wang, T
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1689/1718 631/532/2074 631/61/201 692/700/565/545/576/1955 Adenoviruses Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Animals Apomorphine Applied cell therapy and gene therapy Biological and medical sciences Biomedical and Life Sciences Biomedicine Biotechnology Care and treatment Cell Biology Cell Differentiation Cells, Cultured Corpus Striatum - metabolism Dependovirus - genetics Dopamine - metabolism Dopamine receptors Female Fundamental and applied biological sciences. Psychology Gene Expression Gene Therapy Gene Transfer Techniques Genetic Vectors Glial fibrillary acidic protein Health aspects Health. Pharmaceutical industry Human Genetics Humans Hydroxylase Industrial applications and implications. Economical aspects Medical sciences Mesenchymal Stem Cell Transplantation Mesenchymal stem cells Mesenchymal Stromal Cells - metabolism Movement disorders Nanotechnology Neostriatum Nestin Neural stem cells Neurodegenerative diseases Neuronal-glial interactions Neurons Neuroprotection original-article Parkinson Disease - therapy Parkinson's disease Phosphopyruvate hydratase Physiological aspects Rats Rats, Sprague-Dawley Rotenone Stem cell transplantation Stem cells Substantia nigra Transfusions. Complications. Transfusion reactions. Cell and gene therapy Tyrosine 3-monooxygenase Umbilical cord Umbilical Cord - cytology Vascular endothelial growth factor Vascular Endothelial Growth Factors - genetics Vascular Endothelial Growth Factors - metabolism
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