Particle stimulation dephosphorylates glutathione S-transferase pi 1 of epithelial cells

Abstract Environmental pollutant exposure is associated with adverse respiratory outcomes. The phosphorylation of enzymes activates or deactivates many cellular processes and is related to the development of lung diseases such as asthma and chronic obstructive pulmonary disease. However, little is k...

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Veröffentlicht in:	Toxicology (Amsterdam) 2011-06, Vol.284 (1), p.12-18
Hauptverfasser:	Kim, Tae-Hoon, Jang, An-Soo, Lee, Tae-Hyeong, Kim, Yoon-Jeong, Lee, Eun-Ju, Kim, Jin-Moo, Park, Jong-Sook, Park, Sung-Woo, Park, Choon-Sik
Format:	Artikel
Sprache:	eng
Schlagworte:	2D gel electrophoresis antibodies apoptosis asthma Biological and medical sciences cytoskeletal proteins Emergency epithelial cells gels genes Glutathione S-transferase P1-1 glutathione transferase immunoblotting Medical sciences oxidation particulates phosphoproteins Phosphorylation pollutants precipitin tests protein phosphorylation Proteomics quantitative analysis respiratory mucosa serine signal transduction Titanium dioxide Toxicology two-dimensional gel electrophoresis tyrosine
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