Genetic selection for body weight in chickens has altered responses of the brain's AMPK system to food intake regulation effect of ghrelin, but not obestatin

► Effects of ghrelin/obestatin in high or low body weight chickens investigated. ► Ghrelin decreased food intake at lower doses in the low- than high-weight line. ► Obestatin caused an increase in food intake in high but not low-weight line. ► Ghrelin differentially inhibited AMPK gene expression in...

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Veröffentlicht in:	Behavioural brain research 2011-08, Vol.221 (1), p.216-226
Hauptverfasser:	Xu, Pingwen, Siegel, Paul B., Denbow, D. Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetyl-CoA Carboxylase - metabolism Age Factors AMP-Activated Protein Kinases - metabolism AMPK Animals Appetite Regulation Behavioral psychophysiology Biological and medical sciences Body Weight - genetics Body Weight - physiology Chick Chickens Drinking - drug effects Drinking - genetics Drinking - physiology Eating - drug effects Eating - genetics Eating - physiology Fundamental and applied biological sciences. Psychology Ghrelin Ghrelin - administration & dosage Ghrelin - pharmacology Ghrelin - physiology Hyperphagic Hypophagic Hypothalamus - drug effects Hypothalamus - enzymology Injections, Intraventricular Male Obestain Phosphorylation Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Receptors, Ghrelin - biosynthesis Selection, Genetic - physiology Signal Transduction - drug effects Signal Transduction - genetics
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