Near-infrared spectroscopy (NIRS) and chemometric analysis of Malaysian and UK paracetamol tablets: A spectral database study

[Display omitted] ► We create the spectral database of purchased paracetamol tablets. ► We validate the use of database search algorithms for sample identification. ► We examine the use of database for monitoring of product quality. ► The variability of NIR spectra of paracetamol tablets depends on...

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Veröffentlicht in:	International journal of pharmaceutics 2011-08, Vol.415 (1), p.102-109
Hauptverfasser:	Said, Mazlina M., Gibbons, Simon, Moffat, Anthony C., Zloh, Mire
Format:	Artikel
Sprache:	eng
Schlagworte:	acetaminophen Acetaminophen - analysis Acetaminophen - chemistry active ingredients Algorithms Analgesics, Non-Narcotic - analysis Analgesics, Non-Narcotic - chemistry Biological and medical sciences Chemometrics confidence interval Counterfeit Drugs - analysis Counterfeit Drugs - chemistry Counterfeit medicines Databases, Factual Developing Countries Drug Industry - methods Drug Industry - standards General pharmacology health services ibuprofen Malaysia Medical sciences Models, Chemical near-infrared spectroscopy NIRS Paracetamol PCA Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Principal Component Analysis Qualitative study Quality Control SIMCA Spectral database Spectroscopy, Near-Infrared - methods Tablets United Kingdom
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