Endoglin (CD105): A Review of its Role in Angiogenesis and Tumor Diagnosis, Progression and Therapy

Endoglin (CD105) is an accessory receptor for transforming growth factor beta (TGF-β) and its expression is up-regulated in actively proliferating endothelial cells. Endoglin has been suggested as an appropriate marker for tumor-related angiogenesis and neovascularization. Several studies demonstrat...

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Veröffentlicht in:	Anticancer research 2011-06, Vol.31 (6), p.2283-2290
Hauptverfasser:	NASSIRI, Farshad, CUSIMANO, Michael D, SCHEITHAUER, Bernd W, ROTONDO, Fabio, FAZIO, Alessandra, YOUSEF, George M, SYRO, Luis V, KOVACS, Kalman, LLOYD, Ricardo V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - metabolism Biological and medical sciences Endoglin Humans Medical sciences Neoplasms - blood supply Neoplasms - metabolism Neovascularization, Pathologic - metabolism Receptors, Cell Surface - metabolism Tumors
Online-Zugang:	Volltext
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