De novo protein structure prediction by dynamic fragment assembly and conformational space annealing

Ab initio protein structure prediction is a challenging problem that requires both an accurate energetic representation of a protein structure and an efficient conformational sampling method for successful protein modeling. In this article, we present an ab initio structure prediction method which c...

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Veröffentlicht in:	Proteins, structure, function, and bioinformatics structure, function, and bioinformatics, 2011-08, Vol.79 (8), p.2403-2417
Hauptverfasser:	Lee, Juyong, Lee, Jinhyuk, Sasaki, Takeshi N., Sasai, Masaki, Seok, Chaok, Lee, Jooyoung
Format:	Artikel
Sprache:	eng
Schlagworte:	ab initio protein structure prediction Algorithms conformational space annealing energy parameter optimization fragment assembly Protein Conformation Proteins - chemistry template-free modeling
Online-Zugang:	Volltext
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