Clinical Evaluation of Two Ke0 in the same Pharmacokinetic Propofol Model: Study on Loss and Recovery of Consciousness

The constant equilibrium between the plasma and effect site (ke0) is used by pharmacokinetic models to calculate a drug concentration in its site of action (Ce). It would be interesting if Ce of propofol was similar at loss and recovery of consciousness. The objective of this study was to evaluate t...

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Veröffentlicht in:	Revista brasileira de anestesiologia 2011-07, Vol.61 (4), p.397-408
Hauptverfasser:	Simoni, Ricardo Francisco, Esteves, Luis Otávio, Miziara, Luiz Eduardo de Paula Gomes, Cangiani, Luiz Marciano, Alves, Gustavo Groth Oliveira, Romano, André Luz Pereira, Hansen, Paula Úrica, Vianna, Pedro Thadeu Galvão
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult ANESTÉSICO, Venoso: propofol ANESTÉSICOS, Venoso Bomba de Infusão COMPLICACIONES: despertar intraoperatorio Consciousness - drug effects Drug Delivery Systems EQUIPAMENTOS FARMACOLOGIA Humans Hypnotics and Sedatives - pharmacokinetics Intraoperative Awareness Male Models, Biological Pharmacokinetics Propofol - pharmacokinetics Propofol, administration and dosage
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