Interferon-λ Mediates Oral Tolerance and Inhibits Antigen-Specific, T-Helper 2 Cell–Mediated Inflammation in Mouse Intestine

Background & Aims Oral tolerance is an important component of gastrointestinal homeostasis, but mechanisms of its development are not fully understood. Loss of oral tolerance occurs during food allergen–related inflammation in the gastrointestinal tract. Interferon (IFN)-λ regulates immunity, bu...

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Veröffentlicht in:	Gastroenterology (New York, N.Y. 1943) N.Y. 1943), 2011-07, Vol.141 (1), p.249-258.e2
Hauptverfasser:	He, Shao–Heng, Chen, Xiao, Song, Chun–Hua, Liu, Zhi–Qiang, Zhou, Lin–Fu, Ma, Wen–Jing, Zhao, Lei–Di, Li, Tong–Li, Tang, Shang–Guo, Xing, Zhou, Yang, Ping–Chang
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Blotting, Western CD3 Complex - immunology Cells, Cultured Cytokines - immunology Dendritic Cells - immunology Disease Models, Animal Enteritis - genetics Enteritis - immunology Enteritis - pathology Enteritis - prevention & control Flow Cytometry Food Allergy Gastroenterology and Hepatology Genes, T-Cell Receptor Immune Response Immune Tolerance Immunity, Mucosal Immunohistochemistry Intestines - immunology Intestines - pathology Mice Mice, Inbred BALB C Mice, Transgenic Mouth Mucosa - immunology Mucosal Immunity Ovalbumin Phagocytosis Receptors, Cytokine - immunology Th2 Cells - immunology Th2 Cells - pathology Th2 Cells - transplantation Treg Cells
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