Serum tryptase level is a better predictor of systemic side effects than prostaglandin D2 metabolites during venom immunotherapy in children

We performed a prospective study to analyze mast cell mediators as predictors of systemic adverse reactions during rush venom-specific immunotherapy (VIT) in children. Nineteen children aged 5-17 years received VIT with Venomenhal (HALAllergy). We analyzed serum tryptase (CAP, Phadia), plasma prosta...

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Veröffentlicht in:	Journal of investigational allergology & clinical immunology 2011, Vol.21 (4), p.260-269
Hauptverfasser:	Cichocka-Jarosz, E, Sanak, M, Szczeklik, A, Brzyski, P, Gielicz, A, Pietrzyk, J J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Bee Venoms - adverse effects Bee Venoms - immunology Bee Venoms - therapeutic use Biomarkers Child Child, Preschool Desensitization, Immunologic - adverse effects Desensitization, Immunologic - methods Dinoprost - blood Dinoprost - secretion Dinoprost - urine Emergencies Female Humans Hypersensitivity, Immediate - complications Hypersensitivity, Immediate - etiology Hypersensitivity, Immediate - immunology Hypersensitivity, Immediate - metabolism Male Mast Cells - secretion Peak Expiratory Flow Rate Prospective Studies Prostaglandin D2 - analogs & derivatives Prostaglandin D2 - blood Prostaglandin D2 - secretion Prostaglandin D2 - urine Tryptases - blood Wasp Venoms - adverse effects Wasp Venoms - immunology Wasp Venoms - therapeutic use
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