Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins
Background: This was the long‐term follow‐up of a previously reported randomized clinical trial comparing endovenous laser ablation (EVLA) with cryostripping for great saphenous varicose veins. Methods: A total of 120 patients with great saphenous varicose veins were randomized 1:1 to EVLA or cryost...
Gespeichert in:
| Veröffentlicht in: | British journal of surgery 2011-08, Vol.98 (8), p.1107-1111 |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 1111 |
|---|---|
| container_issue | 8 |
| container_start_page | 1107 |
| container_title | British journal of surgery |
| container_volume | 98 |
| creator | Disselhoff, B. C. V. M. der Kinderen, D. J. Kelder, J. C. Moll, F. L. |
| description | Background:
This was the long‐term follow‐up of a previously reported randomized clinical trial comparing endovenous laser ablation (EVLA) with cryostripping for great saphenous varicose veins.
Methods:
A total of 120 patients with great saphenous varicose veins were randomized 1:1 to EVLA or cryostripping. Principal outcome measures were freedom from incompetence or neovascularization on duplex imaging, and improvement in Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Severity Score (AVVSS) 5 years after treatment.
Results:
Life‐table analysis showed freedom from duplex‐derived incompetence and neovascularization at 5 years in 62 (95 per cent confidence interval 50 to 76) per cent after EVLA and in 51 (39 to 66) per cent after cryostripping (P = 0·246). Neovascularization was more common after cryostripping, but incompetent tributaries were more common after EVLA. VCSS and AVVSS values improved significantly after treatment in both groups, and were maintained for 5 years, but with no significant difference between the groups.
Conclusion:
In this study, no significant difference was demonstrated in late outcome after EVLA or cryostripping in patients with great saphenous varicose veins. Registration number: ISRCTN33832691 (http://www.controlled‐trials.com). Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No difference |
| doi_str_mv | 10.1002/bjs.7542 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_874895404</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>874895404</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3892-6ad7154febe0f2079e83ff6162a8064eb600310d12fe40a07bdd47de0db0a4c03</originalsourceid><addsrcrecordid>eNpF0c1u1DAQAGALgehSkHgC5AvilDL-SZw90oq2oAokfoTUizWJJ61LEqd2dsvyCH1qvNqlvcwc5pvRaIax1wKOBIB839ykI1Nq-YQthKrKQoqqfsoWAGAKoaQ6YC9SugEQCkr5nB3kulJLXS_Y_alfU7EhjDxSWvVz4qHjyCOOLgz-Lzne9n70LfZ8jj7HNgwTRj9eccpkTWNYJd5josix6XH2YeR3fr7mbdyElHumaYu7EPlVJJx5wul617XOc9qQiK_Jj-kle9Zhn-jVPh-yn6cff5ycFxdfzz6dfLgoWlUvZVGhM6LUHTUEnQSzpFp1XSUqiTVUmpoKQAlwQnakAcE0zmnjCFwDqFtQh-zdbu4Uw-2K0mwHn1rqexwpb2Vro-tlqUFn-WYvV81Azk7RDxg39v_5Mni7B5jyhbp8tdanR6eV1nmn7Iqdu_M9bR7qAuz2fTa_z27fZ48_f9_mR-_TTH8ePMbftjLKlPbXlzN7CaL-BseX1qh_gwSeQw</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>874895404</pqid></control><display><type>article</type><title>Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins</title><source>Wiley Online Library - AutoHoldings Journals</source><source>MEDLINE</source><source>Oxford University Press Journals All Titles (1996-Current)</source><creator>Disselhoff, B. C. V. M. ; der Kinderen, D. J. ; Kelder, J. C. ; Moll, F. L.</creator><creatorcontrib>Disselhoff, B. C. V. M. ; der Kinderen, D. J. ; Kelder, J. C. ; Moll, F. L.</creatorcontrib><description>Background:
This was the long‐term follow‐up of a previously reported randomized clinical trial comparing endovenous laser ablation (EVLA) with cryostripping for great saphenous varicose veins.
Methods:
A total of 120 patients with great saphenous varicose veins were randomized 1:1 to EVLA or cryostripping. Principal outcome measures were freedom from incompetence or neovascularization on duplex imaging, and improvement in Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Severity Score (AVVSS) 5 years after treatment.
Results:
Life‐table analysis showed freedom from duplex‐derived incompetence and neovascularization at 5 years in 62 (95 per cent confidence interval 50 to 76) per cent after EVLA and in 51 (39 to 66) per cent after cryostripping (P = 0·246). Neovascularization was more common after cryostripping, but incompetent tributaries were more common after EVLA. VCSS and AVVSS values improved significantly after treatment in both groups, and were maintained for 5 years, but with no significant difference between the groups.
Conclusion:
In this study, no significant difference was demonstrated in late outcome after EVLA or cryostripping in patients with great saphenous varicose veins. Registration number: ISRCTN33832691 (http://www.controlled‐trials.com). Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No difference</description><identifier>ISSN: 0007-1323</identifier><identifier>EISSN: 1365-2168</identifier><identifier>DOI: 10.1002/bjs.7542</identifier><identifier>PMID: 21633948</identifier><identifier>CODEN: BJSUAM</identifier><language>eng</language><publisher>Chichester, UK: John Wiley & Sons, Ltd</publisher><subject>Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cryosurgery - methods ; Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous ; Endovascular Procedures - methods ; Follow-Up Studies ; General aspects ; Humans ; Kaplan-Meier Estimate ; Laser Therapy - methods ; Medical sciences ; Neovascularization, Pathologic - prevention & control ; Quality-Adjusted Life Years ; Saphenous Vein ; Secondary Prevention ; Treatment Outcome ; Varicose Veins - therapy ; Venous Insufficiency - therapy</subject><ispartof>British journal of surgery, 2011-08, Vol.98 (8), p.1107-1111</ispartof><rights>Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3892-6ad7154febe0f2079e83ff6162a8064eb600310d12fe40a07bdd47de0db0a4c03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fbjs.7542$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fbjs.7542$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27903,27904,45553,45554</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24344064$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21633948$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Disselhoff, B. C. V. M.</creatorcontrib><creatorcontrib>der Kinderen, D. J.</creatorcontrib><creatorcontrib>Kelder, J. C.</creatorcontrib><creatorcontrib>Moll, F. L.</creatorcontrib><title>Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins</title><title>British journal of surgery</title><addtitle>Br J Surg</addtitle><description>Background:
This was the long‐term follow‐up of a previously reported randomized clinical trial comparing endovenous laser ablation (EVLA) with cryostripping for great saphenous varicose veins.
Methods:
A total of 120 patients with great saphenous varicose veins were randomized 1:1 to EVLA or cryostripping. Principal outcome measures were freedom from incompetence or neovascularization on duplex imaging, and improvement in Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Severity Score (AVVSS) 5 years after treatment.
Results:
Life‐table analysis showed freedom from duplex‐derived incompetence and neovascularization at 5 years in 62 (95 per cent confidence interval 50 to 76) per cent after EVLA and in 51 (39 to 66) per cent after cryostripping (P = 0·246). Neovascularization was more common after cryostripping, but incompetent tributaries were more common after EVLA. VCSS and AVVSS values improved significantly after treatment in both groups, and were maintained for 5 years, but with no significant difference between the groups.
Conclusion:
In this study, no significant difference was demonstrated in late outcome after EVLA or cryostripping in patients with great saphenous varicose veins. Registration number: ISRCTN33832691 (http://www.controlled‐trials.com). Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No difference</description><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Cryosurgery - methods</subject><subject>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</subject><subject>Endovascular Procedures - methods</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Humans</subject><subject>Kaplan-Meier Estimate</subject><subject>Laser Therapy - methods</subject><subject>Medical sciences</subject><subject>Neovascularization, Pathologic - prevention & control</subject><subject>Quality-Adjusted Life Years</subject><subject>Saphenous Vein</subject><subject>Secondary Prevention</subject><subject>Treatment Outcome</subject><subject>Varicose Veins - therapy</subject><subject>Venous Insufficiency - therapy</subject><issn>0007-1323</issn><issn>1365-2168</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpF0c1u1DAQAGALgehSkHgC5AvilDL-SZw90oq2oAokfoTUizWJJ61LEqd2dsvyCH1qvNqlvcwc5pvRaIax1wKOBIB839ykI1Nq-YQthKrKQoqqfsoWAGAKoaQ6YC9SugEQCkr5nB3kulJLXS_Y_alfU7EhjDxSWvVz4qHjyCOOLgz-Lzne9n70LfZ8jj7HNgwTRj9eccpkTWNYJd5josix6XH2YeR3fr7mbdyElHumaYu7EPlVJJx5wul617XOc9qQiK_Jj-kle9Zhn-jVPh-yn6cff5ycFxdfzz6dfLgoWlUvZVGhM6LUHTUEnQSzpFp1XSUqiTVUmpoKQAlwQnakAcE0zmnjCFwDqFtQh-zdbu4Uw-2K0mwHn1rqexwpb2Vro-tlqUFn-WYvV81Azk7RDxg39v_5Mni7B5jyhbp8tdanR6eV1nmn7Iqdu_M9bR7qAuz2fTa_z27fZ48_f9_mR-_TTH8ePMbftjLKlPbXlzN7CaL-BseX1qh_gwSeQw</recordid><startdate>201108</startdate><enddate>201108</enddate><creator>Disselhoff, B. C. V. M.</creator><creator>der Kinderen, D. J.</creator><creator>Kelder, J. C.</creator><creator>Moll, F. L.</creator><general>John Wiley & Sons, Ltd</general><general>Wiley</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201108</creationdate><title>Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins</title><author>Disselhoff, B. C. V. M. ; der Kinderen, D. J. ; Kelder, J. C. ; Moll, F. L.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3892-6ad7154febe0f2079e83ff6162a8064eb600310d12fe40a07bdd47de0db0a4c03</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Cryosurgery - methods</topic><topic>Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous</topic><topic>Endovascular Procedures - methods</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Humans</topic><topic>Kaplan-Meier Estimate</topic><topic>Laser Therapy - methods</topic><topic>Medical sciences</topic><topic>Neovascularization, Pathologic - prevention & control</topic><topic>Quality-Adjusted Life Years</topic><topic>Saphenous Vein</topic><topic>Secondary Prevention</topic><topic>Treatment Outcome</topic><topic>Varicose Veins - therapy</topic><topic>Venous Insufficiency - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Disselhoff, B. C. V. M.</creatorcontrib><creatorcontrib>der Kinderen, D. J.</creatorcontrib><creatorcontrib>Kelder, J. C.</creatorcontrib><creatorcontrib>Moll, F. L.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Disselhoff, B. C. V. M.</au><au>der Kinderen, D. J.</au><au>Kelder, J. C.</au><au>Moll, F. L.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins</atitle><jtitle>British journal of surgery</jtitle><addtitle>Br J Surg</addtitle><date>2011-08</date><risdate>2011</risdate><volume>98</volume><issue>8</issue><spage>1107</spage><epage>1111</epage><pages>1107-1111</pages><issn>0007-1323</issn><eissn>1365-2168</eissn><coden>BJSUAM</coden><abstract>Background:
This was the long‐term follow‐up of a previously reported randomized clinical trial comparing endovenous laser ablation (EVLA) with cryostripping for great saphenous varicose veins.
Methods:
A total of 120 patients with great saphenous varicose veins were randomized 1:1 to EVLA or cryostripping. Principal outcome measures were freedom from incompetence or neovascularization on duplex imaging, and improvement in Venous Clinical Severity Score (VCSS) and Aberdeen Varicose Vein Severity Score (AVVSS) 5 years after treatment.
Results:
Life‐table analysis showed freedom from duplex‐derived incompetence and neovascularization at 5 years in 62 (95 per cent confidence interval 50 to 76) per cent after EVLA and in 51 (39 to 66) per cent after cryostripping (P = 0·246). Neovascularization was more common after cryostripping, but incompetent tributaries were more common after EVLA. VCSS and AVVSS values improved significantly after treatment in both groups, and were maintained for 5 years, but with no significant difference between the groups.
Conclusion:
In this study, no significant difference was demonstrated in late outcome after EVLA or cryostripping in patients with great saphenous varicose veins. Registration number: ISRCTN33832691 (http://www.controlled‐trials.com). Copyright © 2011 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.
No difference</abstract><cop>Chichester, UK</cop><pub>John Wiley & Sons, Ltd</pub><pmid>21633948</pmid><doi>10.1002/bjs.7542</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0007-1323 |
| ispartof | British journal of surgery, 2011-08, Vol.98 (8), p.1107-1111 |
| issn | 0007-1323 1365-2168 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_874895404 |
| source | Wiley Online Library - AutoHoldings Journals; MEDLINE; Oxford University Press Journals All Titles (1996-Current) |
| subjects | Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cryosurgery - methods Diseases of the peripheral vessels. Diseases of the vena cava. Miscellaneous Endovascular Procedures - methods Follow-Up Studies General aspects Humans Kaplan-Meier Estimate Laser Therapy - methods Medical sciences Neovascularization, Pathologic - prevention & control Quality-Adjusted Life Years Saphenous Vein Secondary Prevention Treatment Outcome Varicose Veins - therapy Venous Insufficiency - therapy |
| title | Five-year results of a randomized clinical trial comparing endovenous laser ablation with cryostripping for great saphenous varicose veins |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-26T11%3A01%3A49IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Five-year%20results%20of%20a%20randomized%20clinical%20trial%20comparing%20endovenous%20laser%20ablation%20with%20cryostripping%20for%20great%20saphenous%20varicose%20veins&rft.jtitle=British%20journal%20of%20surgery&rft.au=Disselhoff,%20B.%20C.%20V.%20M.&rft.date=2011-08&rft.volume=98&rft.issue=8&rft.spage=1107&rft.epage=1111&rft.pages=1107-1111&rft.issn=0007-1323&rft.eissn=1365-2168&rft.coden=BJSUAM&rft_id=info:doi/10.1002/bjs.7542&rft_dat=%3Cproquest_pubme%3E874895404%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=874895404&rft_id=info:pmid/21633948&rfr_iscdi=true |