Hyperlipidemic Guinea Pig Model: Mechanisms of Triglyceride Metabolism Disorder and Comparison to Rat

Guinea pigs and rats are both common animal models for hyperlipidemia studies. However, many recent studies have suggested that rats do not develop hypertriglyceridemia in response to cholesterol feeding. In the present work, the differences in triglyceride metabolism between guinea pigs and rats we...

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Veröffentlicht in:	Biological & Pharmaceutical Bulletin 2011/07/01, Vol.34(7), pp.1046-1051
Hauptverfasser:	Yang, Runmei, Guo, Peng, Song, Xin, Liu, Fang, Gao, Nannan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Base Sequence Dietary Fats - administration & dosage Disease Models, Animal DNA Primers fatty acid β-oxidation guinea pig Guinea Pigs Hyperlipidemias - metabolism Lipids - blood Liver - metabolism Polymerase Chain Reaction rat Rats triglyceride Triglycerides - metabolism very-low-density lipoprotein-triglyceride secretion
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