mTOR and the differentiation of mesenchymal stem cells

The mammalian target of rapamycin （mTOR）, an evolutionarily conserved serine-threonine protein kinase, belongs to the phosphoinositide 3-kinase （PI3K）-related kinase family, which contains a lipid kinase-like domain within their C-terminal region. Recent studies have revealed that mTOR as a critical...

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Veröffentlicht in:	Acta biochimica et biophysica Sinica 2011-07, Vol.43 (7), p.501-510
Hauptverfasser:	Xiang, Xinxin, Zhao, Jing, Xu, Geyang, Li, Yin, Zhang, Weizhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipogenesis - drug effects Animals Cell Differentiation - drug effects Cell Lineage Cell Proliferation - drug effects Humans Mesenchymal Stromal Cells - physiology MicroRNAs - physiology mTOR Muscle Development - drug effects Osteogenesis - drug effects Signal Transduction - physiology Sirolimus - pharmacology TOR Serine-Threonine Kinases - physiology 成骨细胞组织细胞肌肉发生脂肪细胞分化苏氨酸蛋白激酶间质干细胞雷帕霉素
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