Pharmacokinetics of a sustained-release dexamethasone intravitreal implant in vitrectomized and nonvitrectomized eyes

To evaluate dexamethasone pharmacokinetics after implantation of a sustained-release dexamethasone (DEX) intravitreal implant in nonvitrectomized and vitrectomized eyes. The right eyes of 25 rabbits underwent vitrectomy; contralateral eyes served as nonvitrectomy controls. The 0.7-mg DEX implant was...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Investigative ophthalmology & visual science 2011-06, Vol.52 (7), p.4605-4609
Hauptverfasser:	Chang-Lin, Joan-En, Burke, James A, Peng, Qing, Lin, Ton, Orilla, Werhner C, Ghosn, Corine R, Zhang, Kai-Ming, Kuppermann, Baruch D, Robinson, Michael R, Whitcup, Scott M, Welty, Devin F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Delayed-Action Preparations - administration & dosage Delayed-Action Preparations - pharmacokinetics Dexamethasone - administration & dosage Dexamethasone - pharmacokinetics Disease Models, Animal Drug Implants Eye Diseases - drug therapy Eye Diseases - metabolism Eye Diseases - surgery Follow-Up Studies Glucocorticoids - administration & dosage Glucocorticoids - pharmacokinetics Male Metabolic Clearance Rate Posterior Eye Segment Rabbits Vitrectomy Vitreous Body - drug effects Vitreous Body - metabolism Vitreous Body - surgery
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!