Molecular imaging with SPECT as a tool for drug development

Molecular imaging techniques are increasingly being used as valuable tools in the drug development process. Radionuclide-based imaging modalities such as single-photon emission computed tomography (SPECT) and positron emission tomography (PET) have proven to be useful in phases ranging from preclini...

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Veröffentlicht in:	Advanced drug delivery reviews 2011-06, Vol.63 (7), p.547-554
Hauptverfasser:	Gomes, Célia M., Abrunhosa, Antero J., Ramos, Pedro, Pauwels, Ernest K.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Clinical trials Clinical Trials as Topic - methods Dose-Response Relationship, Drug Drug Design Drug development Drug Evaluation, Preclinical - methods Drugs, Investigational - administration & dosage Drugs, Investigational - pharmacokinetics Humans Imaging biomarkers Microdosing Pharmacokinetics Positron-Emission Tomography - methods SPECT Tissue Distribution Tomography, Emission-Computed, Single-Photon - methods
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