Chronic Myeloid Leukemia: A Historical Perspective

Patients with splenomegaly and abnormally high leukocyte counts were first recognized in France, Germany, and Scotland in the 1840s. The only well-documented therapy in the 19th century was use of arsenic in one or other form, which did undoubtedly reduce the leukocyte count but probably did little...

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Veröffentlicht in:	Seminars in hematology 2010-10, Vol.47 (4), p.302-311
1. Verfasser:	Goldman, John M
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - history Antineoplastic Agents - therapeutic use Hematology, Oncology and Palliative Medicine History, 18th Century History, 19th Century History, 20th Century History, 21st Century Humans Leukemia, Myelogenous, Chronic, BCR-ABL Positive - genetics Leukemia, Myelogenous, Chronic, BCR-ABL Positive - history Leukemia, Myelogenous, Chronic, BCR-ABL Positive - therapy Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Protein-Tyrosine Kinases - antagonists & inhibitors Stem Cell Transplantation Transplantation, Homologous
Online-Zugang:	Volltext
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