Characterization of a high-spin non-heme Fe(III)-OOH intermediate and its quantitative conversion to an Fe(IV)═O complex
We have generated a high-spin Fe(III)-OOH complex supported by tetramethylcyclam via protonation of its conjugate base and characterized it in detail using various spectroscopic methods. This Fe(III)-OOH species can be converted quantitatively to an Fe(IV)═O complex via O-O bond cleavage; this is th...
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| Veröffentlicht in: | Journal of the American Chemical Society 2011-05, Vol.133 (19), p.7256-7259 |
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| container_issue | 19 |
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| container_title | Journal of the American Chemical Society |
| container_volume | 133 |
| creator | Li, Feifei Meier, Katlyn K Cranswick, Matthew A Chakrabarti, Mrinmoy Van Heuvelen, Katherine M Münck, Eckard Que, Lawrence |
| description | We have generated a high-spin Fe(III)-OOH complex supported by tetramethylcyclam via protonation of its conjugate base and characterized it in detail using various spectroscopic methods. This Fe(III)-OOH species can be converted quantitatively to an Fe(IV)═O complex via O-O bond cleavage; this is the first example of such a conversion. This conversion is promoted by two factors: the strong Fe(III)-OOH bond, which inhibits Fe-O bond lysis, and the addition of protons, which facilitates O-O bond cleavage. This example provides a synthetic precedent for how O-O bond cleavage of high-spin Fe(III)-peroxo intermediates of non-heme iron enzymes may be promoted. |
| doi_str_mv | 10.1021/ja111742z |
| format | Article |
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This Fe(III)-OOH species can be converted quantitatively to an Fe(IV)═O complex via O-O bond cleavage; this is the first example of such a conversion. This conversion is promoted by two factors: the strong Fe(III)-OOH bond, which inhibits Fe-O bond lysis, and the addition of protons, which facilitates O-O bond cleavage. 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| issn | 1520-5126 |
| language | eng |
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| source | ACS Publications; MEDLINE |
| subjects | Heme - chemistry Iron - chemistry Molecular Structure Organometallic Compounds Oxygen - chemistry |
| title | Characterization of a high-spin non-heme Fe(III)-OOH intermediate and its quantitative conversion to an Fe(IV)═O complex |
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