Chronic kidney disease growth factors in renal fibrosis

Summary 1. The common pathological alteration in virtually every progressive chronic kidney disease (CKD) is renal fibrosis. 2. This review focuses on some growth factors, which are particularly well‐established in contributing to fibrosis, such as the profibrotic, transforming growth factor‐β, and...

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Veröffentlicht in:	Clinical and experimental pharmacology & physiology 2011-07, Vol.38 (7), p.441-450
Hauptverfasser:	Boor, Peter, Floege, Jürgen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals bone morphogenic protein 7 connective tissue growth factor Connective Tissue Growth Factor - metabolism Fibrosis growth factors Humans Intercellular Signaling Peptides and Proteins - metabolism Kidney - metabolism Kidney - pathology Kidney Failure, Chronic - metabolism Kidney Failure, Chronic - pathology platelet-derived growth factor transforming growth factor-β vascular endothelial growth factor
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