Repertoire of microglial and macrophage responses after spinal cord injury

Key Points Macrophages derived from the peripheral circulation and from resident microglia are among the main effectors of the inflammatory response after spinal cord injury. Activated macrophages/microglia in the injured spinal cord contribute to secondary tissue damage through generation of reacti...

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Veröffentlicht in:	Nature reviews. Neuroscience 2011-07, Vol.12 (7), p.388-399
Hauptverfasser:	David, Samuel, Kroner, Antje
Format:	Artikel
Sprache:	eng
Schlagworte:	631/378/1687/1825 692/698/1543/1565/342/1952 Animal Genetics and Genomics Animals Anti-inflammatory drugs Behavioral Sciences Biological and medical sciences Biological Techniques Biomedical and Life Sciences Biomedicine Bone marrow Cell Polarity - physiology Chemokines Dendritic cells Diseases of the osteoarticular system Diseases of the spine Drug therapy Fundamental and applied biological sciences. Psychology Health aspects Humans Inflammation - etiology Inflammation - pathology Macrophages Macrophages - classification Macrophages - physiology Medical sciences Microglia - physiology Models, Biological Morphology Motor control and motor pathways. Reflexes. Control centers of vegetative functions. Vestibular system and equilibration Neurobiology Neurosciences Physiological aspects review-article Spinal cord injuries Spinal Cord Injuries - complications Spinal Cord Injuries - pathology Trauma Tumor necrosis factor-TNF Vertebrates: nervous system and sense organs
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