Succinylcholine use in adult anesthesia - A multinational questionnaire survey
There are no definitive evidence based standards regarding use of succinylcholine (SCh) for anesthesia induction. However, there is a global trend toward eliminating SCh not only in elective, but also in emergency surgery in adults. The aim of the study was to survey the use of SCh in adult elective...
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| Veröffentlicht in: | Collegium antropologicum 2011-01, Vol.35 Suppl 1 (Supp. 1), p.183-190 |
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| creator | Karanović, Nenad Carev, Mladen Kardum, Goran Tomanović, Nikac Stuth, Eckehard Gal, Janos Tonković-Capin, Mislav Dogas, Varja Racić, Goran Dogas, Zoran |
| description | There are no definitive evidence based standards regarding use of succinylcholine (SCh) for anesthesia induction. However, there is a global trend toward eliminating SCh not only in elective, but also in emergency surgery in adults. The aim of the study was to survey the use of SCh in adult elective and emergency anesthesia practice in several European countries and the United States by questionnaire. One hundred and seventy anesthesiologists out of 201 possible, from six institutions in five countries (Croatia, Bosnia and Herzegovina, Hungary, United Kingdom, and the United States) anonymously completed the questionnaire about their use of SCh. The questionnaire was structured to assess the respondents': frequency of use of SCh in adult surgery (elective and emergency), reasons for use or rejection of SCh, positive and negative attributes of SCh, and observed side effects in their practice. Differences in use were tested using X2-test when appropriate. There was a significant difference in the use of SCh between countries for elective surgery with the lower use in UK and Hungary (chi2=45.8, p |
| format | Article |
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However, there is a global trend toward eliminating SCh not only in elective, but also in emergency surgery in adults. The aim of the study was to survey the use of SCh in adult elective and emergency anesthesia practice in several European countries and the United States by questionnaire. One hundred and seventy anesthesiologists out of 201 possible, from six institutions in five countries (Croatia, Bosnia and Herzegovina, Hungary, United Kingdom, and the United States) anonymously completed the questionnaire about their use of SCh. The questionnaire was structured to assess the respondents': frequency of use of SCh in adult surgery (elective and emergency), reasons for use or rejection of SCh, positive and negative attributes of SCh, and observed side effects in their practice. Differences in use were tested using X2-test when appropriate. There was a significant difference in the use of SCh between countries for elective surgery with the lower use in UK and Hungary (chi2=45.8, p <0.001). One hundred and seventeen (69%) use it regularly. In emergency surgery 165 (97%) anesthesiologists use it without any significant difference among countries (chi2=2.13, p<0.711). The top indications for SCh use were anticipated difficult intubation/ventilation (74%), caesarean section (54%), and obesity and/or hiatus hernia (49%). The top reasons against SCh use were adequate substitutes (87%), fear of arrhythmias (45%), and anaphylaxis (19%). The most desirable reported drug features were: rapid onset (88%), short duration (64%), and effective relaxation (61%). Forty-six per cent of the surveyed anesthesiologists stated they had never experienced a complication with its use. The most frequently reported side effects were myalgias (47%), bradycardias (42%), and prolonged blockade (39%). Allergic reactions were reported by 13%, and asystole by 12% of physicians. From our survey it is possible to conclude that succinylcholine is still regularly used, at least by surveyed anesthesiologists in Europe and USA, in adult anesthesia practice, especially in elective surgery for which it may be least suited. This reflects the discrepancies between the international guidelines for the use of SCh and the clinical practice of many anesthesiologists in different countries. The regional differences in SCh usage may be considered through anesthesia cultures and practice variations depending on country.</description><identifier>ISSN: 0350-6134</identifier><identifier>PMID: 21648332</identifier><language>eng</language><publisher>Croatia</publisher><subject>Adult ; Anesthesia, General - methods ; Anesthetics - administration & dosage ; Culture ; Europe ; Europe, Eastern ; Female ; Health care ; Humans ; Male ; Medicine ; Neuromuscular Depolarizing Agents - administration & dosage ; Succinylcholine - administration & dosage ; Survey analysis ; Surveys and Questionnaires ; U.S.A ; United Kingdom ; United States</subject><ispartof>Collegium antropologicum, 2011-01, Vol.35 Suppl 1 (Supp. 1), p.183-190</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21648332$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Karanović, Nenad</creatorcontrib><creatorcontrib>Carev, Mladen</creatorcontrib><creatorcontrib>Kardum, Goran</creatorcontrib><creatorcontrib>Tomanović, Nikac</creatorcontrib><creatorcontrib>Stuth, Eckehard</creatorcontrib><creatorcontrib>Gal, Janos</creatorcontrib><creatorcontrib>Tonković-Capin, Mislav</creatorcontrib><creatorcontrib>Dogas, Varja</creatorcontrib><creatorcontrib>Racić, Goran</creatorcontrib><creatorcontrib>Dogas, Zoran</creatorcontrib><title>Succinylcholine use in adult anesthesia - A multinational questionnaire survey</title><title>Collegium antropologicum</title><addtitle>Coll Antropol</addtitle><description>There are no definitive evidence based standards regarding use of succinylcholine (SCh) for anesthesia induction. However, there is a global trend toward eliminating SCh not only in elective, but also in emergency surgery in adults. The aim of the study was to survey the use of SCh in adult elective and emergency anesthesia practice in several European countries and the United States by questionnaire. One hundred and seventy anesthesiologists out of 201 possible, from six institutions in five countries (Croatia, Bosnia and Herzegovina, Hungary, United Kingdom, and the United States) anonymously completed the questionnaire about their use of SCh. The questionnaire was structured to assess the respondents': frequency of use of SCh in adult surgery (elective and emergency), reasons for use or rejection of SCh, positive and negative attributes of SCh, and observed side effects in their practice. Differences in use were tested using X2-test when appropriate. There was a significant difference in the use of SCh between countries for elective surgery with the lower use in UK and Hungary (chi2=45.8, p <0.001). One hundred and seventeen (69%) use it regularly. In emergency surgery 165 (97%) anesthesiologists use it without any significant difference among countries (chi2=2.13, p<0.711). The top indications for SCh use were anticipated difficult intubation/ventilation (74%), caesarean section (54%), and obesity and/or hiatus hernia (49%). The top reasons against SCh use were adequate substitutes (87%), fear of arrhythmias (45%), and anaphylaxis (19%). The most desirable reported drug features were: rapid onset (88%), short duration (64%), and effective relaxation (61%). Forty-six per cent of the surveyed anesthesiologists stated they had never experienced a complication with its use. The most frequently reported side effects were myalgias (47%), bradycardias (42%), and prolonged blockade (39%). Allergic reactions were reported by 13%, and asystole by 12% of physicians. From our survey it is possible to conclude that succinylcholine is still regularly used, at least by surveyed anesthesiologists in Europe and USA, in adult anesthesia practice, especially in elective surgery for which it may be least suited. This reflects the discrepancies between the international guidelines for the use of SCh and the clinical practice of many anesthesiologists in different countries. The regional differences in SCh usage may be considered through anesthesia cultures and practice variations depending on country.</description><subject>Adult</subject><subject>Anesthesia, General - methods</subject><subject>Anesthetics - administration & dosage</subject><subject>Culture</subject><subject>Europe</subject><subject>Europe, Eastern</subject><subject>Female</subject><subject>Health care</subject><subject>Humans</subject><subject>Male</subject><subject>Medicine</subject><subject>Neuromuscular Depolarizing Agents - administration & dosage</subject><subject>Succinylcholine - administration & dosage</subject><subject>Survey analysis</subject><subject>Surveys and Questionnaires</subject><subject>U.S.A</subject><subject>United Kingdom</subject><subject>United States</subject><issn>0350-6134</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkM1LxDAQxXNQ3HX1X5DcPBXy1TQ9LotfsOhBPZdpM2UjaVqbRtj_3qDr3cNjhjc_hsc7I2smS1ZoLtWKXMb4wVhZaaYvyEpwrYyUYk2eX1PXuXD03WH0LiBNEakLFGzyC4WAcTlgdEALuqVD9lyAxY0BPP1M-ZjXAG5GGtP8hccrct6Dj3h9mhvyfn_3tnss9i8PT7vtvph4JZZCGlSyVb2WHLUwYE3P2qxetqxS1gAT3NYCAIw1tbGdqbVm2EutOOtKlBty-_t3msefHM3gYofe58Rjio2pJOeVEvU_SM5LXjKRyZsTmdoBbTPNboD52PyVJb8Bc31lDA</recordid><startdate>201101</startdate><enddate>201101</enddate><creator>Karanović, Nenad</creator><creator>Carev, Mladen</creator><creator>Kardum, Goran</creator><creator>Tomanović, Nikac</creator><creator>Stuth, Eckehard</creator><creator>Gal, Janos</creator><creator>Tonković-Capin, Mislav</creator><creator>Dogas, Varja</creator><creator>Racić, Goran</creator><creator>Dogas, Zoran</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope><scope>8BJ</scope><scope>FQK</scope><scope>JBE</scope></search><sort><creationdate>201101</creationdate><title>Succinylcholine use in adult anesthesia - A multinational questionnaire survey</title><author>Karanović, Nenad ; Carev, Mladen ; Kardum, Goran ; Tomanović, Nikac ; Stuth, Eckehard ; Gal, Janos ; Tonković-Capin, Mislav ; Dogas, Varja ; Racić, Goran ; Dogas, Zoran</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p172t-38e43b4f631e628ad8f0b8f0f3b074d8a021d92aaa8d898dc89660ef36410c5e3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Adult</topic><topic>Anesthesia, General - methods</topic><topic>Anesthetics - administration & dosage</topic><topic>Culture</topic><topic>Europe</topic><topic>Europe, Eastern</topic><topic>Female</topic><topic>Health care</topic><topic>Humans</topic><topic>Male</topic><topic>Medicine</topic><topic>Neuromuscular Depolarizing Agents - administration & dosage</topic><topic>Succinylcholine - administration & dosage</topic><topic>Survey analysis</topic><topic>Surveys and Questionnaires</topic><topic>U.S.A</topic><topic>United Kingdom</topic><topic>United States</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Karanović, Nenad</creatorcontrib><creatorcontrib>Carev, Mladen</creatorcontrib><creatorcontrib>Kardum, Goran</creatorcontrib><creatorcontrib>Tomanović, Nikac</creatorcontrib><creatorcontrib>Stuth, Eckehard</creatorcontrib><creatorcontrib>Gal, Janos</creatorcontrib><creatorcontrib>Tonković-Capin, Mislav</creatorcontrib><creatorcontrib>Dogas, Varja</creatorcontrib><creatorcontrib>Racić, Goran</creatorcontrib><creatorcontrib>Dogas, Zoran</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><collection>International Bibliography of the Social Sciences (IBSS)</collection><collection>International Bibliography of the Social Sciences</collection><collection>International Bibliography of the Social Sciences</collection><jtitle>Collegium antropologicum</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Karanović, Nenad</au><au>Carev, Mladen</au><au>Kardum, Goran</au><au>Tomanović, Nikac</au><au>Stuth, Eckehard</au><au>Gal, Janos</au><au>Tonković-Capin, Mislav</au><au>Dogas, Varja</au><au>Racić, Goran</au><au>Dogas, Zoran</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Succinylcholine use in adult anesthesia - A multinational questionnaire survey</atitle><jtitle>Collegium antropologicum</jtitle><addtitle>Coll Antropol</addtitle><date>2011-01</date><risdate>2011</risdate><volume>35 Suppl 1</volume><issue>Supp. 1</issue><spage>183</spage><epage>190</epage><pages>183-190</pages><issn>0350-6134</issn><abstract>There are no definitive evidence based standards regarding use of succinylcholine (SCh) for anesthesia induction. However, there is a global trend toward eliminating SCh not only in elective, but also in emergency surgery in adults. The aim of the study was to survey the use of SCh in adult elective and emergency anesthesia practice in several European countries and the United States by questionnaire. One hundred and seventy anesthesiologists out of 201 possible, from six institutions in five countries (Croatia, Bosnia and Herzegovina, Hungary, United Kingdom, and the United States) anonymously completed the questionnaire about their use of SCh. The questionnaire was structured to assess the respondents': frequency of use of SCh in adult surgery (elective and emergency), reasons for use or rejection of SCh, positive and negative attributes of SCh, and observed side effects in their practice. Differences in use were tested using X2-test when appropriate. There was a significant difference in the use of SCh between countries for elective surgery with the lower use in UK and Hungary (chi2=45.8, p <0.001). One hundred and seventeen (69%) use it regularly. In emergency surgery 165 (97%) anesthesiologists use it without any significant difference among countries (chi2=2.13, p<0.711). The top indications for SCh use were anticipated difficult intubation/ventilation (74%), caesarean section (54%), and obesity and/or hiatus hernia (49%). The top reasons against SCh use were adequate substitutes (87%), fear of arrhythmias (45%), and anaphylaxis (19%). The most desirable reported drug features were: rapid onset (88%), short duration (64%), and effective relaxation (61%). Forty-six per cent of the surveyed anesthesiologists stated they had never experienced a complication with its use. The most frequently reported side effects were myalgias (47%), bradycardias (42%), and prolonged blockade (39%). Allergic reactions were reported by 13%, and asystole by 12% of physicians. From our survey it is possible to conclude that succinylcholine is still regularly used, at least by surveyed anesthesiologists in Europe and USA, in adult anesthesia practice, especially in elective surgery for which it may be least suited. This reflects the discrepancies between the international guidelines for the use of SCh and the clinical practice of many anesthesiologists in different countries. The regional differences in SCh usage may be considered through anesthesia cultures and practice variations depending on country.</abstract><cop>Croatia</cop><pmid>21648332</pmid><tpages>8</tpages></addata></record> |
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| subjects | Adult Anesthesia, General - methods Anesthetics - administration & dosage Culture Europe Europe, Eastern Female Health care Humans Male Medicine Neuromuscular Depolarizing Agents - administration & dosage Succinylcholine - administration & dosage Survey analysis Surveys and Questionnaires U.S.A United Kingdom United States |
| title | Succinylcholine use in adult anesthesia - A multinational questionnaire survey |
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