Comparison of the Pharmacokinetics of a New 15-mg Modified-Release Tablet Formulation of Metoclopramide Versus a 10-mg Immediate-Release Tablet: A Single- and Multiple-Dose, Randomized, Open-Label, Parallel-Group Study in Healthy Mexican Male Volunteers

Abstract Background Metoclopramide is a prokinetic and antiemetic agent. Objective The goal of this study was to assess the pharmacokinetics of a new, modified-release metoclopramide tablet and compare it with an immediate-release tablet to obtain marketing approval from the Mexican regulatory agenc...

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Veröffentlicht in:	Clinical therapeutics 2011-05, Vol.33 (5), p.630-643
Hauptverfasser:	Bernardo-Escudero, Roberto, MD, MSc, Alonso-Campero, Rosalba, MD, MSc, de Jesús Francisco-Doce, María Teresa, PharmD, MSc, Cortés-Fuentes, Myriam, PharmD, Villa-Vargas, Miriam, PharmD, Ángeles-Uribe, Juan, PharmD, MSc
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Antiemetics - pharmacokinetics bioavailability Biological and medical sciences Biological Availability Blood & organ donations Body mass index Dosage Forms Drug dosages Drug therapy healthy subjects Humans immediate-release Internal Medicine Male Medical Education Medical sciences metoclopramide Metoclopramide - pharmacokinetics modified-release pharmacokinetics Pharmacology. Drug treatments Reference Values Studies Tablets
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