Changes in glandular and stromal estrogen and progesterone receptor isoform expression in eutopic and ectopic endometrium following treatment with the levonorgestrel-releasing intrauterine system

Abstract Objectives The levonorgestrel (LNG) intrauterine system (LNG-IUS) has been shown to improve symptoms in women with minimal to moderate endometriosis. The precise mechanism for this is unknown. We hypothesized that this involves alteration in the expression of estrogen receptors (ER) and pro...

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Veröffentlicht in:	European journal of obstetrics & gynecology and reproductive biology 2011-07, Vol.157 (1), p.101-106
Hauptverfasser:	Engemise, Samuel L, Willets, Jonathon M, Taylor, Anthony H, Emembolu, Joseph O, Konje, Justin C
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Biological and medical sciences Biopsy Down-Regulation - drug effects Drug Delivery Systems Endometriosis Endometriosis - drug therapy Endometriosis - metabolism Endometriosis - pathology Endometrium Endometrium - drug effects Endometrium - metabolism Endometrium - pathology Estrogen receptor (ER) Female Female genital diseases Follicular Phase - metabolism Gynecology. Andrology. Obstetrics Humans Immunohistochemistry Levonorgestrel - administration & dosage Levonorgestrel - therapeutic use Levonorgestrel intrauterine system (LNG-IUS) Luteal Phase - metabolism Medical sciences Non tumoral diseases Obstetrics and Gynecology Progesterone receptor (PR) Protein Isoforms - metabolism Receptors, Estrogen - metabolism Receptors, Progesterone - metabolism Severity of Illness Index Young Adult
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