Secreted autotransporter toxin (Sat) triggers autophagy in epithelial cells that relies on cell detachment

Summary The secreted autotransporter toxin, Sat, which belongs to the subfamily of serine protease autotransporters of Enterobacteriaceae, acts as a virulence factor in extraintestinal and intestinal pathogenic strains of Escherichia coli. We observed that HeLa cells exposed to the cell‐free culture...

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Veröffentlicht in:	Cellular microbiology 2011-07, Vol.13 (7), p.992-1013
Hauptverfasser:	Liévin‐Le Moal, Vanessa, Comenge, Yannick, Ruby, Vincent, Amsellem, Raymonde, Nicolas, Valérie, Servin, Alain L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Autophagy Bacterial Toxins Cell Adhesion Cytoskeleton - metabolism Enterobacteriaceae Epithelial Cells - microbiology Epithelial Cells - physiology Escherichia coli Escherichia coli - pathogenicity Escherichia coli Proteins - secretion Fibroblasts - microbiology HeLa Cells Humans Mice Signal Transduction Virulence Factors - metabolism
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