The Utility of ERG/P63 Double Immunohistochemical Staining in the Diagnosis of Limited Cancer in Prostate Needle Biopsies

Diagnosis of limited cancer can be challenging in prostate needle biopsies, and immunohistochemistry is commonly used in such settings. Recently, TMPRSS2:ERG gene rearrangement was found to be highly specific for and detected in approximately 50% of prostate cancer. Positive immunohistochemical stai...

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Veröffentlicht in:	The American journal of surgical pathology 2011-07, Vol.35 (7), p.1062-1068
Hauptverfasser:	YASKIV, Oksana, XIAOCHUN ZHANG, SIMMERMAN, Kelly, DALY, Tom, HUIYING HE, FALZARANO, Sara, LONGWEN CHEN, MAGI-GALLUZZI, Cristina, MING ZHOU
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - diagnosis Adenocarcinoma - metabolism Biological and medical sciences Biomarkers, Tumor - metabolism Biopsy, Needle Endothelium, Vascular - metabolism Endothelium, Vascular - pathology Gynecology. Andrology. Obstetrics Humans Immunohistochemistry - methods Investigative techniques, diagnostic techniques (general aspects) Male Male genital diseases Medical sciences Nephrology. Urinary tract diseases Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Prostatic Intraepithelial Neoplasia - diagnosis Prostatic Intraepithelial Neoplasia - metabolism Prostatic Neoplasms - diagnosis Prostatic Neoplasms - metabolism Trans-Activators - metabolism Transcription Factors - metabolism Transcriptional Regulator ERG Tumor Suppressor Proteins - metabolism Tumors Tumors of the urinary system Urinary tract. Prostate gland
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