Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior
► (PhSe) 2 attenuated spontaneous activity, number of vocalizations and jumps in chicks. ► At the dose of 10 mg/kg, (PhSe) 2 caused an anxiolytic-like effect in chicks. ► Anxiolytic-like and sedative effects were observed in chicks treated with (PhSe) 2 50 mg/kg. The purpose of this research was to...
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| Veröffentlicht in: | Neuroscience letters 2011-05, Vol.495 (2), p.140-143 |
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| creator | Prigol, Marina Luchese, Cristiane Pinton, Simone Ferreira, Marlise Santos, João Paulo Aquino Karkow, Ana Kátia Mortari, Antonio Carlos Nogueira, Cristina Wayne |
| description | ► (PhSe)
2 attenuated spontaneous activity, number of vocalizations and jumps in chicks. ► At the dose of 10
mg/kg, (PhSe)
2 caused an anxiolytic-like effect in chicks. ► Anxiolytic-like and sedative effects were observed in chicks treated with (PhSe)
2 50
mg/kg.
The purpose of this research was to investigate the anxiolytic-like effect of diphenyl diselenide [(PhSe)
2] on the chick social separation-stress behavior. Male chicks (six day-old) received, per oral route, a single administration of (PhSe)
2 at doses of 1, 10 and 50
mg/kg. Thirty minutes after treatment, chicks were submitted to the behavioral tests. The behavioral tests: number of separation-induced distress vocalizations and jumps, time of active wakefulness, time of standing/sitting motionless with eyes open, time of standing motionless with eyes closed and time of sleeping posture, during 10
min, were recorded. (PhSe)
2 at doses of 10 and 50
mg/kg reduced the number of vocalizations and jumps and the time of active wakefulness and increased the time of standing/sitting motionless with eyes open of chicks. The sleeping posture time was increased in animals treated with (PhSe)
2 at the dose of 50
mg/kg. In conclusion, treatment with (PhSe)
2, in a dose dependent-manner, caused anxiolytic-like and sedative effects in chicks. |
| doi_str_mv | 10.1016/j.neulet.2011.03.057 |
| format | Article |
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2 attenuated spontaneous activity, number of vocalizations and jumps in chicks. ► At the dose of 10
mg/kg, (PhSe)
2 caused an anxiolytic-like effect in chicks. ► Anxiolytic-like and sedative effects were observed in chicks treated with (PhSe)
2 50
mg/kg.
The purpose of this research was to investigate the anxiolytic-like effect of diphenyl diselenide [(PhSe)
2] on the chick social separation-stress behavior. Male chicks (six day-old) received, per oral route, a single administration of (PhSe)
2 at doses of 1, 10 and 50
mg/kg. Thirty minutes after treatment, chicks were submitted to the behavioral tests. The behavioral tests: number of separation-induced distress vocalizations and jumps, time of active wakefulness, time of standing/sitting motionless with eyes open, time of standing motionless with eyes closed and time of sleeping posture, during 10
min, were recorded. (PhSe)
2 at doses of 10 and 50
mg/kg reduced the number of vocalizations and jumps and the time of active wakefulness and increased the time of standing/sitting motionless with eyes open of chicks. The sleeping posture time was increased in animals treated with (PhSe)
2 at the dose of 50
mg/kg. In conclusion, treatment with (PhSe)
2, in a dose dependent-manner, caused anxiolytic-like and sedative effects in chicks.</description><identifier>ISSN: 0304-3940</identifier><identifier>EISSN: 1872-7972</identifier><identifier>DOI: 10.1016/j.neulet.2011.03.057</identifier><identifier>PMID: 21443928</identifier><identifier>CODEN: NELED5</identifier><language>eng</language><publisher>Shannon: Elsevier Ireland Ltd</publisher><subject>Animals ; Anti-Anxiety Agents - pharmacology ; Anti-Anxiety Agents - therapeutic use ; Anxiolytic-like ; Behavior, Animal - drug effects ; Benzene Derivatives - pharmacology ; Benzene Derivatives - therapeutic use ; Biological and medical sciences ; Chickens ; Chicks ; Diphenyl diselenide ; Dose-Response Relationship, Drug ; Fundamental and applied biological sciences. Psychology ; Hypnotics and Sedatives - pharmacology ; Hypnotics and Sedatives - therapeutic use ; Male ; Medical sciences ; Neuropharmacology ; Organoselenium Compounds - pharmacology ; Organoselenium Compounds - therapeutic use ; Pharmacology. Drug treatments ; Psycholeptics: tranquillizer, neuroleptic ; Psychology. Psychoanalysis. Psychiatry ; Psychopharmacology ; Sedative ; Selenium ; Social Isolation ; Stress, Psychological - prevention & control ; Stress, Psychological - psychology ; Vertebrates: nervous system and sense organs</subject><ispartof>Neuroscience letters, 2011-05, Vol.495 (2), p.140-143</ispartof><rights>2011 Elsevier Ireland Ltd</rights><rights>2015 INIST-CNRS</rights><rights>Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-82520def257ea292c70a8ec598473055cbc7dcb29d90b7ade9144202d6ac99d43</citedby><cites>FETCH-LOGICAL-c423t-82520def257ea292c70a8ec598473055cbc7dcb29d90b7ade9144202d6ac99d43</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.neulet.2011.03.057$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,780,784,3541,27915,27916,45986</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24143105$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21443928$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Prigol, Marina</creatorcontrib><creatorcontrib>Luchese, Cristiane</creatorcontrib><creatorcontrib>Pinton, Simone</creatorcontrib><creatorcontrib>Ferreira, Marlise</creatorcontrib><creatorcontrib>Santos, João Paulo Aquino</creatorcontrib><creatorcontrib>Karkow, Ana Kátia</creatorcontrib><creatorcontrib>Mortari, Antonio Carlos</creatorcontrib><creatorcontrib>Nogueira, Cristina Wayne</creatorcontrib><title>Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior</title><title>Neuroscience letters</title><addtitle>Neurosci Lett</addtitle><description>► (PhSe)
2 attenuated spontaneous activity, number of vocalizations and jumps in chicks. ► At the dose of 10
mg/kg, (PhSe)
2 caused an anxiolytic-like effect in chicks. ► Anxiolytic-like and sedative effects were observed in chicks treated with (PhSe)
2 50
mg/kg.
The purpose of this research was to investigate the anxiolytic-like effect of diphenyl diselenide [(PhSe)
2] on the chick social separation-stress behavior. Male chicks (six day-old) received, per oral route, a single administration of (PhSe)
2 at doses of 1, 10 and 50
mg/kg. Thirty minutes after treatment, chicks were submitted to the behavioral tests. The behavioral tests: number of separation-induced distress vocalizations and jumps, time of active wakefulness, time of standing/sitting motionless with eyes open, time of standing motionless with eyes closed and time of sleeping posture, during 10
min, were recorded. (PhSe)
2 at doses of 10 and 50
mg/kg reduced the number of vocalizations and jumps and the time of active wakefulness and increased the time of standing/sitting motionless with eyes open of chicks. The sleeping posture time was increased in animals treated with (PhSe)
2 at the dose of 50
mg/kg. In conclusion, treatment with (PhSe)
2, in a dose dependent-manner, caused anxiolytic-like and sedative effects in chicks.</description><subject>Animals</subject><subject>Anti-Anxiety Agents - pharmacology</subject><subject>Anti-Anxiety Agents - therapeutic use</subject><subject>Anxiolytic-like</subject><subject>Behavior, Animal - drug effects</subject><subject>Benzene Derivatives - pharmacology</subject><subject>Benzene Derivatives - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Chickens</subject><subject>Chicks</subject><subject>Diphenyl diselenide</subject><subject>Dose-Response Relationship, Drug</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Hypnotics and Sedatives - pharmacology</subject><subject>Hypnotics and Sedatives - therapeutic use</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Neuropharmacology</subject><subject>Organoselenium Compounds - pharmacology</subject><subject>Organoselenium Compounds - therapeutic use</subject><subject>Pharmacology. Drug treatments</subject><subject>Psycholeptics: tranquillizer, neuroleptic</subject><subject>Psychology. Psychoanalysis. Psychiatry</subject><subject>Psychopharmacology</subject><subject>Sedative</subject><subject>Selenium</subject><subject>Social Isolation</subject><subject>Stress, Psychological - prevention & control</subject><subject>Stress, Psychological - psychology</subject><subject>Vertebrates: nervous system and sense organs</subject><issn>0304-3940</issn><issn>1872-7972</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp90E1rFDEYwPEgil2r30AkF-lpxicvszO5CFJrFQpe2nPIJM-w2WaTNZlZ3G9vyq566ykEfk9e_oS8Z9AyYOtP2zbiEnBuOTDWgmih61-QFRt63vSq5y_JCgTIRigJF-RNKVsA6FgnX5MLzqQUig8rkr76_QbjMVDnCwaM3iH10S0WCzXxt0_hOHvbBP-Ide9oQWdmf0CK04R2LjRFOm-Q2o23j7Qk602oaG9yZSk2Zc5YCh1xYw4-5bfk1WRCwXfn9ZI8fLu5v_7e3P28_XH95a6xkou5GXjHweHEux4NV9z2YAa0nRpkL6Dr7Gh7Z0eunIKxNw5V_REH7tbGKuWkuCRXp3P3Of1asMx654vFEEzEtBRdKzEhYM2rlCdpcyol46T32e9MPmoG-qm03upTaf1UWoPQtXQd-3C-YBl36P4N_U1bwcczMMWaMGUTrS__nWRSMOiq-3xyWHMcPGZdrMdo0flcA2uX_PMv-QOW6KAd</recordid><startdate>20110516</startdate><enddate>20110516</enddate><creator>Prigol, Marina</creator><creator>Luchese, Cristiane</creator><creator>Pinton, Simone</creator><creator>Ferreira, Marlise</creator><creator>Santos, João Paulo Aquino</creator><creator>Karkow, Ana Kátia</creator><creator>Mortari, Antonio Carlos</creator><creator>Nogueira, Cristina Wayne</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QG</scope><scope>7TK</scope></search><sort><creationdate>20110516</creationdate><title>Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior</title><author>Prigol, Marina ; Luchese, Cristiane ; Pinton, Simone ; Ferreira, Marlise ; Santos, João Paulo Aquino ; Karkow, Ana Kátia ; Mortari, Antonio Carlos ; Nogueira, Cristina Wayne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-82520def257ea292c70a8ec598473055cbc7dcb29d90b7ade9144202d6ac99d43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2011</creationdate><topic>Animals</topic><topic>Anti-Anxiety Agents - pharmacology</topic><topic>Anti-Anxiety Agents - therapeutic use</topic><topic>Anxiolytic-like</topic><topic>Behavior, Animal - drug effects</topic><topic>Benzene Derivatives - pharmacology</topic><topic>Benzene Derivatives - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Chickens</topic><topic>Chicks</topic><topic>Diphenyl diselenide</topic><topic>Dose-Response Relationship, Drug</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Hypnotics and Sedatives - pharmacology</topic><topic>Hypnotics and Sedatives - therapeutic use</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Neuropharmacology</topic><topic>Organoselenium Compounds - pharmacology</topic><topic>Organoselenium Compounds - therapeutic use</topic><topic>Pharmacology. Drug treatments</topic><topic>Psycholeptics: tranquillizer, neuroleptic</topic><topic>Psychology. Psychoanalysis. Psychiatry</topic><topic>Psychopharmacology</topic><topic>Sedative</topic><topic>Selenium</topic><topic>Social Isolation</topic><topic>Stress, Psychological - prevention & control</topic><topic>Stress, Psychological - psychology</topic><topic>Vertebrates: nervous system and sense organs</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Prigol, Marina</creatorcontrib><creatorcontrib>Luchese, Cristiane</creatorcontrib><creatorcontrib>Pinton, Simone</creatorcontrib><creatorcontrib>Ferreira, Marlise</creatorcontrib><creatorcontrib>Santos, João Paulo Aquino</creatorcontrib><creatorcontrib>Karkow, Ana Kátia</creatorcontrib><creatorcontrib>Mortari, Antonio Carlos</creatorcontrib><creatorcontrib>Nogueira, Cristina Wayne</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Animal Behavior Abstracts</collection><collection>Neurosciences Abstracts</collection><jtitle>Neuroscience letters</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Prigol, Marina</au><au>Luchese, Cristiane</au><au>Pinton, Simone</au><au>Ferreira, Marlise</au><au>Santos, João Paulo Aquino</au><au>Karkow, Ana Kátia</au><au>Mortari, Antonio Carlos</au><au>Nogueira, Cristina Wayne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior</atitle><jtitle>Neuroscience letters</jtitle><addtitle>Neurosci Lett</addtitle><date>2011-05-16</date><risdate>2011</risdate><volume>495</volume><issue>2</issue><spage>140</spage><epage>143</epage><pages>140-143</pages><issn>0304-3940</issn><eissn>1872-7972</eissn><coden>NELED5</coden><abstract>► (PhSe)
2 attenuated spontaneous activity, number of vocalizations and jumps in chicks. ► At the dose of 10
mg/kg, (PhSe)
2 caused an anxiolytic-like effect in chicks. ► Anxiolytic-like and sedative effects were observed in chicks treated with (PhSe)
2 50
mg/kg.
The purpose of this research was to investigate the anxiolytic-like effect of diphenyl diselenide [(PhSe)
2] on the chick social separation-stress behavior. Male chicks (six day-old) received, per oral route, a single administration of (PhSe)
2 at doses of 1, 10 and 50
mg/kg. Thirty minutes after treatment, chicks were submitted to the behavioral tests. The behavioral tests: number of separation-induced distress vocalizations and jumps, time of active wakefulness, time of standing/sitting motionless with eyes open, time of standing motionless with eyes closed and time of sleeping posture, during 10
min, were recorded. (PhSe)
2 at doses of 10 and 50
mg/kg reduced the number of vocalizations and jumps and the time of active wakefulness and increased the time of standing/sitting motionless with eyes open of chicks. The sleeping posture time was increased in animals treated with (PhSe)
2 at the dose of 50
mg/kg. In conclusion, treatment with (PhSe)
2, in a dose dependent-manner, caused anxiolytic-like and sedative effects in chicks.</abstract><cop>Shannon</cop><pub>Elsevier Ireland Ltd</pub><pmid>21443928</pmid><doi>10.1016/j.neulet.2011.03.057</doi><tpages>4</tpages></addata></record> |
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| ispartof | Neuroscience letters, 2011-05, Vol.495 (2), p.140-143 |
| issn | 0304-3940 1872-7972 |
| language | eng |
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| source | MEDLINE; Elsevier ScienceDirect Journals Complete |
| subjects | Animals Anti-Anxiety Agents - pharmacology Anti-Anxiety Agents - therapeutic use Anxiolytic-like Behavior, Animal - drug effects Benzene Derivatives - pharmacology Benzene Derivatives - therapeutic use Biological and medical sciences Chickens Chicks Diphenyl diselenide Dose-Response Relationship, Drug Fundamental and applied biological sciences. Psychology Hypnotics and Sedatives - pharmacology Hypnotics and Sedatives - therapeutic use Male Medical sciences Neuropharmacology Organoselenium Compounds - pharmacology Organoselenium Compounds - therapeutic use Pharmacology. Drug treatments Psycholeptics: tranquillizer, neuroleptic Psychology. Psychoanalysis. Psychiatry Psychopharmacology Sedative Selenium Social Isolation Stress, Psychological - prevention & control Stress, Psychological - psychology Vertebrates: nervous system and sense organs |
| title | Diphenyl diselenide induces anxiolytic-like and sedative effects on the chick social separation-stress behavior |
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