NONOates–Polyethylenimine Hydrogel for Controlled Nitric Oxide Release and Cell Proliferation Modulation

In recent years, numerous research activities have been devoted to the controlled release of nitric oxide (NO) due to its potential as a restenosis inhibitor which inhibits the proliferation of vascular smooth muscle cells, the apoptosis of vascular endothelial cells, and aggregation of platelets. T...

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Veröffentlicht in:	Bioconjugate chemistry 2011-06, Vol.22 (6), p.1031-1038
Hauptverfasser:	Kim, Jihoon, Lee, Yanggy, Singha, Kaushik, Kim, Hyun Woo, Shin, Jae Ho, Jo, Seongbong, Han, Dong-Keun, Kim, Won Jong
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Azo Compounds - chemistry Binding sites Cell culture Cell Proliferation - drug effects Cells, Cultured Endothelial Cells - cytology Endothelial Cells - drug effects High pressure Humans Hydrogel, Polyethylene Glycol Dimethacrylate - chemistry Models, Molecular Molecular Structure Myocytes, Smooth Muscle - cytology Myocytes, Smooth Muscle - drug effects Nitric oxide Nitric Oxide - metabolism Nitric Oxide - pharmacology Poloxamer - chemistry Polyethyleneimine - chemistry Polymers Protein synthesis Structure-Activity Relationship
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