Clinical and virological course of infection with haemagglutinin D222G mutant strain of 2009 pandemic influenza A (H1N1) virus

Abstract Background Aspartic acid to glycine substitution (D222G) of haemagglutinin subunit (HA1) was associated with adverse outcomes in 2009 pandemic influenza A (H1N1) infections. Objectives To characterize the virological profile and antiviral response of patients infected with the HA1 D222G mut...

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Veröffentlicht in:	Journal of clinical virology 2011-04, Vol.50 (4), p.320-324
Hauptverfasser:	Chan, Paul K.S, Lee, Nelson, Joynt, Gavin M, Choi, K.W, Cheung, Jo L.K, Yeung, Apple C.M, Lam, Philip, Wong, Rity, Leung, Bo-Wah, So, Hing-Yu, Lam, Wai-Yip, Hui, David C.S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Aged, 80 and over Allergy and Immunology Amino Acid Substitution Biological and medical sciences Cohort Studies D222G Female Fundamental and applied biological sciences. Psychology Haemagglutinin Hemagglutinin Glycoproteins, Influenza Virus - genetics Hong Kong - epidemiology Human viral diseases Humans Infectious Disease Infectious diseases Influenza Influenza A Virus, H1N1 Subtype - genetics Influenza A Virus, H1N1 Subtype - immunology Influenza A Virus, H1N1 Subtype - physiology Influenza, Human - epidemiology Influenza, Human - virology Male Medical sciences Microbiology Middle Aged Miscellaneous Mutation Pandemic Pandemics Pneumonia - virology Respiratory System - virology Reverse Transcriptase Polymerase Chain Reaction Sequence Analysis, DNA Tropism Viral diseases Virology Young Adult
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