Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats

Histamine and calcitonin gene-related peptide (CGRP) contribute to the pain perception. The aim of the present study is to clarify the interaction of histamine and CGRP in the perception of inflammatory pain. The effects of a histamine H1 receptor antagonist (pyrilamine, i.p.), an H2 receptor antago...

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Veröffentlicht in:	Biomedical research (Tokyo) 2011-06, Vol.32 (3), p.195-201
Hauptverfasser:	Mobarakeh, Jalal Izadi, Torkaman-Boutorabi, Anahita, Rahimi, Amir Abbas, Ghasri, Shahrooz, Nezhad, Reza Mohammad Ali, Hamzely, Arash, Khoshkholgh Sima, Baharak, Takahashi, Kazuhiro, Nunoki, Kazuo, Yanai, Kazuhiko
Format:	Artikel
Sprache:	eng
Schlagworte:	Analgesics - administration & dosage Analgesics - pharmacology Animals Calcitonin Gene-Related Peptide - administration & dosage Calcitonin Gene-Related Peptide - pharmacology Drug Interactions Drug Therapy, Combination Formaldehyde - adverse effects Histamine - pharmacology Histamine H1 Antagonists - administration & dosage Histamine H1 Antagonists - pharmacology Histamine H2 Antagonists - administration & dosage Histamine H2 Antagonists - pharmacology Hyperalgesia - chemically induced Male Pain - chemically induced Pain - drug therapy Pain Perception - drug effects Peptide Fragments - administration & dosage Peptide Fragments - pharmacology Pyrilamine - administration & dosage Pyrilamine - pharmacology Ranitidine - administration & dosage Ranitidine - pharmacology Rats Rats, Wistar Receptors, Calcitonin Gene-Related Peptide - antagonists & inhibitors
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