Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12
A powder preparation of the oral probiotic Streptococcus salivarius K12 has been given to 19 young otitis media-prone children following a 3-day course of amoxicillin administered as a preliminary to ventilation tube placement. In two subjects, the use of strain K12 appeared to effect the expansion...
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Veröffentlicht in: | European journal of clinical microbiology & infectious diseases 2008-12, Vol.27 (12), p.1261-1263 |
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creator | Power, D. A Burton, J. P Chilcott, C. N Dawes, P. J Tagg, J. R |
description | A powder preparation of the oral probiotic Streptococcus salivarius K12 has been given to 19 young otitis media-prone children following a 3-day course of amoxicillin administered as a preliminary to ventilation tube placement. In two subjects, the use of strain K12 appeared to effect the expansion of an indigenous population of inhibitory S. salivarius. In other children, strain K12 colonisation extended beyond the oral cavity to also include the nasopharynx or adenoid tissue. The relatively low proportion (33%) of subjects that colonised was attributed to failure of the amoxicillin pre-treatment to sufficiently reduce the indigenous S. salivarius populations prior to dosing with strain K12 powder. |
doi_str_mv | 10.1007/s10096-008-0569-4 |
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A ; Burton, J. P ; Chilcott, C. N ; Dawes, P. J ; Tagg, J. R</creator><creatorcontrib>Power, D. A ; Burton, J. P ; Chilcott, C. N ; Dawes, P. J ; Tagg, J. R</creatorcontrib><description>A powder preparation of the oral probiotic Streptococcus salivarius K12 has been given to 19 young otitis media-prone children following a 3-day course of amoxicillin administered as a preliminary to ventilation tube placement. In two subjects, the use of strain K12 appeared to effect the expansion of an indigenous population of inhibitory S. salivarius. In other children, strain K12 colonisation extended beyond the oral cavity to also include the nasopharynx or adenoid tissue. 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In other children, strain K12 colonisation extended beyond the oral cavity to also include the nasopharynx or adenoid tissue. 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subjects | Administration, Oral Amoxicillin - administration & dosage Antibiotics Biological and medical sciences Biomedical and Life Sciences Biomedicine Brief Report Child, Preschool Colonization Ear diseases Humans Infant Infectious diseases Internal Medicine Lymphoid Tissue - microbiology Medical Microbiology Medical sciences Mouth - microbiology Nasopharynx - microbiology Pediatrics Probiotics Probiotics - administration & dosage Respiratory System - microbiology Respiratory tract Streptococcus - growth & development Streptococcus salivarius Surgery Ventilation |
title | Preliminary investigations of the colonisation of upper respiratory tract tissues of infants using a paediatric formulation of the oral probiotic Streptococcus salivarius K12 |
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