An Initial Sustained Inflation Improves the Respiratory and Cardiovascular Transition at Birth in Preterm Lambs

A sustained inflation (SI) facilitates lung aeration after birth but may impair the neonatal cardiovascular transition. We aimed to determine the effect of an initial SI on pulmonary arterial and carotid blood flow (PBF and CBF) after preterm birth. Fetal sheep were instrumented at ∼122 d of gestati...

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Veröffentlicht in:	Pediatric research 2011-07, Vol.70 (1), p.56-60
Hauptverfasser:	Sobotka, Kristina S, Hooper, Stuart B, Allison, Beth J, te Pas, Arjan B, Davis, Peter G, Morley, Colin J, Moss, Timothy J M
Format:	Artikel
Sprache:	eng
Schlagworte:	631/443 692/700/1720 692/700/565 Adaptation, Physiological Animals Animals, Newborn Biological and medical sciences Carbon Dioxide - blood Carotid Arteries - physiopathology Cerebrovascular Circulation Diseases of mother, fetus and pregnancy General aspects Gestational Age Gynecology. Andrology. Obstetrics Hydrogen-Ion Concentration Hyperoxia - etiology Hyperoxia - prevention & control Hypoxia - blood Hypoxia - physiopathology Hypoxia - prevention & control Lung - physiopathology Lung Compliance Medical sciences Medicine Medicine & Public Health Oxygen - blood Pediatric Surgery Pediatrics Pregnancy. Fetus. Placenta Premature Birth Pulmonary Artery - physiopathology Pulmonary Circulation Regional Blood Flow Respiration, Artificial - adverse effects Respiration, Artificial - methods Sheep Tidal Volume Time Factors translational-investigation
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