Up‐regulation and clinical significance of serine protease kallikrein 6 in colon cancer

BACKGROUND: Kallikrein‐related peptidase 6 (KLK6) encodes a trypsin‐like serine protease that is up‐regulated in several cancers, although the putative functions of KLK6 in cancer have not been elucidated. In the current study, overexpression of KLK6 was identified in colon cancer, and the possibili...

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Veröffentlicht in:	Cancer 2011-06, Vol.117 (12), p.2608-2619
Hauptverfasser:	Kim, Jong‐Tae, Song, Eun Young, Chung, Kyung‐Sook, Kang, Min Ah, Kim, Jae Wha, Kim, Sang Jick, Yeom, Young Il, Kim, Joo Heon, Kim, Kyo Hyun, Lee, Hee Gu
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cell Line, Tumor Colon - enzymology colon cancer Colonic Neoplasms - enzymology Colonic Neoplasms - mortality Colonic Neoplasms - pathology Female Gastroenterology. Liver. Pancreas. Abdomen Humans immunohistochemistry invasiveness kallikrein Kallikreins - analysis Kallikreins - genetics Kallikreins - physiology kallikrein‐related peptidase 6 Male Medical sciences Middle Aged Neoplasm Invasiveness Neoplasm Staging Prognosis Proportional Hazards Models RNA, Messenger - analysis Stomach. Duodenum. Small intestine. Colon. Rectum. Anus Tumors Up-Regulation
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