Prefrontal lobe dysfunction predicts treatment response in medication-naive first-episode schizophrenia

Abstract Dysfunction of the frontal lobe is considered to be central to the pathology of schizophrenia. However, the nature of these abnormalities is unclear, in particular whether they are affected by treatment. In an earlier functional MRI study of our group we found dorsolateral prefrontal lobe (...

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Veröffentlicht in:	Schizophrenia research 2011-07, Vol.129 (2), p.156-162
Hauptverfasser:	van Veelen, Nicoletta M.J, Vink, Matthijs, Ramsey, Nick F, van Buuren, Mariët, Hoogendam, Janna Marie, Kahn, René S
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Antipsychotic Agents - therapeutic use Biological and medical sciences Brain Mapping Dorsolateral prefrontal cortex Female fMRI Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging - methods Male Medical sciences Medication-naive Memory, Short-Term - drug effects Memory, Short-Term - physiology Neuropsychological Tests Oxygen Predictive Value of Tests Prefrontal Cortex - blood supply Prefrontal Cortex - drug effects Prefrontal Cortex - physiopathology Psychiatric Status Rating Scales Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Psychoses Reaction Time - drug effects Schizophrenia Schizophrenia - drug therapy Schizophrenia - pathology Treatment Treatment Outcome Treatment response Young Adult
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