A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas

A 78-year-old man presented with upper abdominal pain. He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a s...

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Veröffentlicht in:Nippon Shokakibyo Gakkai Zasshi 2011, Vol.108(6), pp.969-977
Hauptverfasser: SAKEMI, Ryosuke, SO, Suketo, MORIMITSU, Yosuke, UCHIYAMA, Daiji, KAKIUCHI, Seiya, ISHIHARA, Yuji, MATSUSHIMA, Yu, KUBO, Yasuhiko, MATSUGAKI, Satoru, ONO, Tetsujiro, TAKANE, Junko, SASAKI, Ei, SAKEMI, Miyuki, SHIMOKOBE, Masayuki, SATA, Michio
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container_end_page 977
container_issue 6
container_start_page 969
container_title Nippon Shokakibyo Gakkai Zasshi
container_volume 108
creator SAKEMI, Ryosuke
SO, Suketo
MORIMITSU, Yosuke
UCHIYAMA, Daiji
KAKIUCHI, Seiya
ISHIHARA, Yuji
MATSUSHIMA, Yu
KUBO, Yasuhiko
MATSUGAKI, Satoru
ONO, Tetsujiro
TAKANE, Junko
SASAKI, Ei
SAKEMI, Miyuki
SHIMOKOBE, Masayuki
SATA, Michio
description A 78-year-old man presented with upper abdominal pain. He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a surgical biopsy was performed. Histologic studies revealed lymphoplasmacytic sclerosing pancreatitis with significant infiltration of IgG4-positive plasma cells. His serum IgG4 level was 223mg/dl. Findings from histologic and serum studies were compatible with IgG4-related sclerosing disorders. The mass lesions responded to steroid therapy and disappeared. The difficulty in making a definitive diagnosis is discussed.
doi_str_mv 10.11405/nisshoshi.108.969
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subjects Aged
Autoimmune Diseases - pathology
Humans
Immunoglobulin G - analysis
Male
Mesentery - pathology
Pancreatic Diseases - pathology
Pancreatitis - pathology
Sclerosis - pathology
title A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas
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