A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas
A 78-year-old man presented with upper abdominal pain. He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a s...
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Veröffentlicht in: | Nippon Shokakibyo Gakkai Zasshi 2011, Vol.108(6), pp.969-977 |
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creator | SAKEMI, Ryosuke SO, Suketo MORIMITSU, Yosuke UCHIYAMA, Daiji KAKIUCHI, Seiya ISHIHARA, Yuji MATSUSHIMA, Yu KUBO, Yasuhiko MATSUGAKI, Satoru ONO, Tetsujiro TAKANE, Junko SASAKI, Ei SAKEMI, Miyuki SHIMOKOBE, Masayuki SATA, Michio |
description | A 78-year-old man presented with upper abdominal pain. He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a surgical biopsy was performed. Histologic studies revealed lymphoplasmacytic sclerosing pancreatitis with significant infiltration of IgG4-positive plasma cells. His serum IgG4 level was 223mg/dl. Findings from histologic and serum studies were compatible with IgG4-related sclerosing disorders. The mass lesions responded to steroid therapy and disappeared. The difficulty in making a definitive diagnosis is discussed. |
doi_str_mv | 10.11405/nisshoshi.108.969 |
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He underwent an abdominal computed tomography scan which revealed irregularly shaped mass lesions in the mesentery and in the pancreatic head and body. The mass lesions were suspected to be pancreatic cancer with peritoneal dissemination and a surgical biopsy was performed. Histologic studies revealed lymphoplasmacytic sclerosing pancreatitis with significant infiltration of IgG4-positive plasma cells. His serum IgG4 level was 223mg/dl. Findings from histologic and serum studies were compatible with IgG4-related sclerosing disorders. The mass lesions responded to steroid therapy and disappeared. The difficulty in making a definitive diagnosis is discussed.</description><subject>Aged</subject><subject>Autoimmune Diseases - pathology</subject><subject>Humans</subject><subject>Immunoglobulin G - analysis</subject><subject>Male</subject><subject>Mesentery - pathology</subject><subject>Pancreatic Diseases - pathology</subject><subject>Pancreatitis - pathology</subject><subject>Sclerosis - pathology</subject><issn>0446-6586</issn><issn>1349-7693</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2011</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kFFrwjAUhcPYmOL8A3sYfdtTXWLaNHkU2Zwg7MX3kCa3NtKmLrcK_vt10_lyDxw-DtyPkGdGZ4xlNH8LHrHusPYzRuVMCXVHxoxnKi2E4vdkTLNMpCKXYkSmiL6klKpcSc4fyWjORCYKkY_JdpFYg5B0VbLerbI0QmN6cAnaBmKHPuwS57GLDiImPpy65vTb9TUkLSCEHuI5McH9NQcTbASDT-ShMg3C9JoTsv143y4_083Xar1cbNI9k6pPoZybCjJDAYwzjivuWCGtKtlvKSkfHmWFY1BWpeJVLkrKbAXSCgM8t3xCXi-zh9h9HwF73Xq00DQmQHdELQtGh5G5HMiXK3ksW3D6EH1r4ln_exiA1QXYY292cANM7P1gQt9k60G2Ftc7SL8RtjZRQ-A_3Rd94w</recordid><startdate>201106</startdate><enddate>201106</enddate><creator>SAKEMI, Ryosuke</creator><creator>SO, Suketo</creator><creator>MORIMITSU, Yosuke</creator><creator>UCHIYAMA, Daiji</creator><creator>KAKIUCHI, Seiya</creator><creator>ISHIHARA, Yuji</creator><creator>MATSUSHIMA, Yu</creator><creator>KUBO, Yasuhiko</creator><creator>MATSUGAKI, Satoru</creator><creator>ONO, Tetsujiro</creator><creator>TAKANE, Junko</creator><creator>SASAKI, Ei</creator><creator>SAKEMI, Miyuki</creator><creator>SHIMOKOBE, Masayuki</creator><creator>SATA, Michio</creator><general>The Japanese Society of Gastroenterology</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>201106</creationdate><title>A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas</title><author>SAKEMI, Ryosuke ; SO, Suketo ; MORIMITSU, Yosuke ; UCHIYAMA, Daiji ; KAKIUCHI, Seiya ; ISHIHARA, Yuji ; MATSUSHIMA, Yu ; KUBO, Yasuhiko ; MATSUGAKI, Satoru ; ONO, Tetsujiro ; TAKANE, Junko ; SASAKI, Ei ; SAKEMI, Miyuki ; SHIMOKOBE, Masayuki ; SATA, Michio</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-j189t-eb2afe4a0eeadad393d178c9b1e4a080311417d1ebfb93f56b01cfe8c6ae35c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>jpn</language><creationdate>2011</creationdate><topic>Aged</topic><topic>Autoimmune Diseases - pathology</topic><topic>Humans</topic><topic>Immunoglobulin G - analysis</topic><topic>Male</topic><topic>Mesentery - pathology</topic><topic>Pancreatic Diseases - pathology</topic><topic>Pancreatitis - pathology</topic><topic>Sclerosis - pathology</topic><toplevel>online_resources</toplevel><creatorcontrib>SAKEMI, Ryosuke</creatorcontrib><creatorcontrib>SO, Suketo</creatorcontrib><creatorcontrib>MORIMITSU, Yosuke</creatorcontrib><creatorcontrib>UCHIYAMA, Daiji</creatorcontrib><creatorcontrib>KAKIUCHI, Seiya</creatorcontrib><creatorcontrib>ISHIHARA, Yuji</creatorcontrib><creatorcontrib>MATSUSHIMA, Yu</creatorcontrib><creatorcontrib>KUBO, Yasuhiko</creatorcontrib><creatorcontrib>MATSUGAKI, Satoru</creatorcontrib><creatorcontrib>ONO, Tetsujiro</creatorcontrib><creatorcontrib>TAKANE, Junko</creatorcontrib><creatorcontrib>SASAKI, Ei</creatorcontrib><creatorcontrib>SAKEMI, Miyuki</creatorcontrib><creatorcontrib>SHIMOKOBE, Masayuki</creatorcontrib><creatorcontrib>SATA, Michio</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Nippon Shokakibyo Gakkai Zasshi</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>SAKEMI, Ryosuke</au><au>SO, Suketo</au><au>MORIMITSU, Yosuke</au><au>UCHIYAMA, Daiji</au><au>KAKIUCHI, Seiya</au><au>ISHIHARA, Yuji</au><au>MATSUSHIMA, Yu</au><au>KUBO, Yasuhiko</au><au>MATSUGAKI, Satoru</au><au>ONO, Tetsujiro</au><au>TAKANE, Junko</au><au>SASAKI, Ei</au><au>SAKEMI, Miyuki</au><au>SHIMOKOBE, Masayuki</au><au>SATA, Michio</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas</atitle><jtitle>Nippon Shokakibyo Gakkai Zasshi</jtitle><addtitle>Nippon Shokakibyo Gakkai Zasshi</addtitle><date>2011-06</date><risdate>2011</risdate><volume>108</volume><issue>6</issue><spage>969</spage><epage>977</epage><pages>969-977</pages><issn>0446-6586</issn><eissn>1349-7693</eissn><abstract>A 78-year-old man presented with upper abdominal pain. 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subjects | Aged Autoimmune Diseases - pathology Humans Immunoglobulin G - analysis Male Mesentery - pathology Pancreatic Diseases - pathology Pancreatitis - pathology Sclerosis - pathology |
title | A case of IgG4-related sclerosing disorders involving the mesentery and the pancreas |
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