The promotion of microvasculature formation in poly(ethylene glycol) diacrylate hydrogels by an immobilized VEGF-mimetic peptide

Abstract Microvascularization of tissue engineered constructs was achieved by utilizing a VEGF-mimicking peptide, QK, covalently bound to a poly(ethylene glycol) hydrogel matrix. The 15-amino acid peptide, developed by D’Andrea et al., was modified with a PEG-succinimidyl ester linker on the N-termi...

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Veröffentlicht in:	Biomaterials 2011-09, Vol.32 (25), p.5782-5789
Hauptverfasser:	Leslie-Barbick, Julia E, Saik, Jennifer E, Gould, Daniel J, Dickinson, Mary E, West, Jennifer L
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Angiogenesis Animals Cells, Cultured Cornea - blood supply Dentistry Humans Hydrogels - chemistry Mice Microvessels - growth & development Molecular Mimicry Peptide Poly(ethylene glycol) Polyethylene Glycols - chemistry Vascular Endothelial Growth Factor A - chemistry Vascularization
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