Catechol-o-methyltransferase gene modulation on suicidal behavior and personality traits: review, meta-analysis and association study

Abstract Suicide is one of the leading causes of death among young adults. Both genetic and personality factors plausibly have a role on suicidal behavior. We focused on the catechol-O-methyltransferase gene (COMT) and we performed: a review of studies investigating the association between COMT and...

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Veröffentlicht in:	Journal of psychiatric research 2011-03, Vol.45 (3), p.309-321
Hauptverfasser:	Calati, Raffaella, Porcelli, Stefano, Giegling, Ina, Hartmann, Annette M, Möller, Hans-Jürgen, De Ronchi, Diana, Serretti, Alessandro, Rujescu, Dan
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Adult and adolescent clinical studies Aggression Anger Biological and medical sciences Catechol O-methyltransferase Catechol O-Methyltransferase - genetics COMT Emotions Female Gene Frequency Gene polymorphism Genes Genome-Wide Association Study - methods Genotype Humans Inventories Italy Linkage Disequilibrium Male Medical sciences Meta-Analysis as Topic Middle Aged Mood Multivariate Analysis Personality Personality - genetics Personality Inventory Polymorphism, Genetic Psychiatry Psychology. Psychoanalysis. Psychiatry Psychopathology. Psychiatry Reinforcement Reviews Suicidal behaviour Suicide Suicide - psychology Surveys and Questionnaires Temperament Variants
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