Cancer chemoprevention with green tea catechins by targeting receptor tyrosine kinases

Recent studies indicate that receptor tyrosine kinases (RTKs), which play important roles in cell proliferation, are one of the possible targets of green tea catechins (GTCs) in cancer cell growth inhibition. (−)‐Epigallocatechin‐3‐gallate (EGCG), the major catechin in green tea, inhibits cell proli...

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Veröffentlicht in:	Molecular nutrition & food research 2011-06, Vol.55 (6), p.832-843
Hauptverfasser:	Shimizu, Masahito, Adachi, Seiji, Masuda, Muneyuki, Kozawa, Osamu, Moriwaki, Hisataka
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anticarcinogenic Agents - pharmacology Anticarcinogenic Agents - therapeutic use Catechin - pharmacology Catechin - therapeutic use Chemoprevention Colorectal cancer EGCG Hepatocellular carcinoma Humans Lipid rafts Membrane Microdomains - drug effects Membrane Microdomains - metabolism Molecular Targeted Therapy Neoplasms - metabolism Neoplasms - prevention & control Phytotherapy Plant Extracts - chemistry Plant Extracts - pharmacology Plant Extracts - therapeutic use Protein Kinase Inhibitors - pharmacology Protein Kinase Inhibitors - therapeutic use Receptor Protein-Tyrosine Kinases - antagonists & inhibitors Receptor tyrosine kinase Signal Transduction - drug effects Tea - chemistry
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