Reversing microcrystalline tests—An analytical approach to recycling of microcrystals from drugs of abuse

Reversing microcrystalline tests—An analytical approach to recycling of microcrystals from drugs of abuse

Abstract A combined analysis of microcrystalline tests followed by LC–MS or GC–MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was d...

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Veröffentlicht in:Forensic science international 2011-04, Vol.207 (1), p.e55-e58
Hauptverfasser: Elie, Leonie E, Baron, Mark G, Croxton, Ruth S, Elie, Mathieu P
Format: Artikel
Sprache:eng
Schlagworte:
Acids
Analytical chemistry
Calibration
Chromatography
Crystals
Drugs
Drugs of abuse
Forensic chemistry
Forensic science
Forensic sciences
GC–MS
GHB
LC–MS
Mass spectrometry
Mathematical analysis
Methadone
Microcrystalline test
Microcrystals
Nitrates
Nondestructive testing
Pathology
Rape
Recycling
Reversing
Solvents
Studies
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Zusammenfassung:Abstract A combined analysis of microcrystalline tests followed by LC–MS or GC–MS analysis is described. Microcrystalline tests are shown to be non-destructive as addition products formed were easily dissociated after the application of an appropriate solvent. Subsequent analysis of the sample was done to quantify the recovery of the drug. Examples were performed using the date rape drug γ-hydroxybutyrate (GHB) and the synthetic opioid methadone.
ISSN:0379-0738
1872-6283
DOI:10.1016/j.forsciint.2011.01.008