Interstitial lung disease in systemic sclerosis

Abstract Interstitial lung disease (ILD) is a common manifestation of systemic sclerosis (SSc) and mainly encountered in patients with diffuse disease and/or anti-topoisomerase 1 antibodies. ILD develops in up to 75% of patients with SSc overall. However, SSc-ILD evolves to end-stage respiratory ins...

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Veröffentlicht in:	Autoimmunity reviews 2011-03, Vol.10 (5), p.248-255
Hauptverfasser:	Bussone, Guillaume, Mouthon, Luc
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergy and Immunology Antibodies Antibodies, Monoclonal, Murine-Derived - therapeutic use Autoantibodies - immunology Autoantibodies - metabolism azathioprine Azathioprine - therapeutic use Carbon monoxide Computed tomography Contraindications Cyclophosphamide Cyclophosphamide - therapeutic use DNA Topoisomerases, Type I - immunology DNA Topoisomerases, Type I - metabolism Dyspnea Four-Dimensional Computed Tomography Gastroesophageal Reflux - complications Gastroesophageal Reflux - pathology Humans Immunosuppressive agents Immunosuppressive Agents - therapeutic use Interstitial lung disease Lung - immunology Lung - pathology Lung - physiopathology Lung diseases Lung Diseases, Interstitial - diagnosis Lung Diseases, Interstitial - etiology Lung Diseases, Interstitial - immunology Lung Diseases, Interstitial - physiopathology Lung Diseases, Interstitial - therapy Lung Transplantation Mycophenolate mofetil Mycophenolic Acid - analogs & derivatives Mycophenolic Acid - therapeutic use Opportunist infection Pathophysiology Pneumonia Prognosis Pulmonary Fibrosis - complications Pulmonary Fibrosis - pathology Randomized Controlled Trials as Topic Respiration Respiratory Function Tests Rituximab Scleroderma, Systemic - complications Scleroderma, Systemic - diagnosis Scleroderma, Systemic - physiopathology Systemic sclerosis Treatment
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