Quantification of cystatin C in cerebrospinal fluid from various neurological disorders and correlation with G73A polymorphism in CST3

Abstract Cystatin C (CC) is a cysteine protease inhibitor abundantly expressed in the central nervous system. Bunina bodies, small eosinophilic intraneuronal inclusions, are stain positive for CC and are the most specific histological hallmark of amyotrophic lateral sclerosis (ALS). In this study, e...

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Veröffentlicht in:	Brain research 2010-11, Vol.1361, p.140-145
Hauptverfasser:	Yamamoto-Watanabe, Yukiko, Watanabe, Mitsunori, Jackson, Mandy, Akimoto, Hiroyuki, Sugimoto, Kazuhiro, Yasujima, Minoru, Wakasaya, Yasuhito, Matsubara, Etsuro, Kawarabayashi, Takeshi, Harigaya, Yasuo, Lyndon, Alastair R, Shoji, Mikio
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alanine Alzheimer Disease - cerebrospinal fluid Alzheimer Disease - genetics Alzheimer's disease Amyotrophic lateral sclerosis Amyotrophic Lateral Sclerosis - cerebrospinal fluid Amyotrophic Lateral Sclerosis - genetics Biological and medical sciences Biomarkers Case-Control Studies Cerebrospinal fluid Cerebrospinal fluid. Meninges. Spinal cord Cystatin C Cystatin C - blood Cystatin C - cerebrospinal fluid Cystatin C - genetics Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Glycine Humans Immunoassay - methods Latex Male Medical sciences Middle Aged Multiple System Atrophy - cerebrospinal fluid Multiple System Atrophy - genetics Nephelometry and Turbidimetry - methods Nervous system (semeiology, syndromes) Nervous System Diseases - blood Nervous System Diseases - cerebrospinal fluid Nervous System Diseases - genetics Neurological disorder Neurology Parkinson Disease - cerebrospinal fluid Parkinson Disease - genetics Polymorphism, Single Nucleotide Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - cerebrospinal fluid Polyradiculoneuropathy, Chronic Inflammatory Demyelinating - genetics Tauopathies - cerebrospinal fluid Tauopathies - genetics
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