Effect of berberine and Berberis aetnensis C. Presl. alkaloid extract on glutamate-evoked tissue transglutaminase up-regulation in astroglial cell cultures

Berberis aetnensis C. Presl. is a bushy‐spiny shrub common on Mount Etna (Sicily, Italy), containing various alkaloids with several pharmacological properties. This study assessed the effect of berberine and of the alkaloid extract of B. aetnensis roots on the glutamate‐evoked tissue transglutaminas...

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Veröffentlicht in:	Phytotherapy research 2011-06, Vol.25 (6), p.816-820
Hauptverfasser:	Campisi, Agata, Acquaviva, Rosaria, Mastrojeni, Silvana, Raciti, Giuseppina, Vanella, Angelo, De Pasquale, Rita, Puglisi, Salvatore, Iauk, Liliana
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaloids - pharmacology Animals astrocytes Astrocytes - drug effects Astrocytes - enzymology Astrocytes - metabolism berberine Berberine - pharmacology Berberis Berberis - chemistry Berberis aetnensis C. Presl Cells, Cultured excitotoxicity glutamate Glutamic Acid - pharmacology Plant Extracts - pharmacology Plant Roots - chemistry Rats Sicily tissue transglutaminase Transglutaminases - metabolism Up-Regulation - drug effects
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