Diagnostic and Vaccine Chapter
Abstract The first report in this chapter describes the development of a killed composite vaccine. This killed vaccine is non-infectious to humans, other animals, and the environment. The vaccine has low reactivity, is non-abortive, and does not induce pathomorphological alterations to the organs of...
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| Veröffentlicht in: | Vaccine 2010-10, Vol.28 (S5), p.F49-F53 |
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| container_issue | S5 |
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| container_title | Vaccine |
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| creator | Wolfram, J.H Kokanov, S.K Verkhovsky, O.A |
| description | Abstract The first report in this chapter describes the development of a killed composite vaccine. This killed vaccine is non-infectious to humans, other animals, and the environment. The vaccine has low reactivity, is non-abortive, and does not induce pathomorphological alterations to the organs of vaccinated animals. The second report of this chapter describes the diagnostic value of a competitive enzyme-linked immunosorbent assay for detecting Brucella -specific antibodies and its ability to discriminate vaccinated cattle from infected cattle. The results indicated that the competitive enzyme-linked immunosorbent assay is more sensitive than traditional tests for detecting antibodies to Brucella abortus in naturally and experimentally infected cattle. |
| doi_str_mv | 10.1016/j.vaccine.2010.04.051 |
| format | Article |
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This killed vaccine is non-infectious to humans, other animals, and the environment. The vaccine has low reactivity, is non-abortive, and does not induce pathomorphological alterations to the organs of vaccinated animals. The second report of this chapter describes the diagnostic value of a competitive enzyme-linked immunosorbent assay for detecting Brucella -specific antibodies and its ability to discriminate vaccinated cattle from infected cattle. The results indicated that the competitive enzyme-linked immunosorbent assay is more sensitive than traditional tests for detecting antibodies to Brucella abortus in naturally and experimentally infected cattle.</description><identifier>ISSN: 0264-410X</identifier><identifier>EISSN: 1873-2518</identifier><identifier>DOI: 10.1016/j.vaccine.2010.04.051</identifier><identifier>PMID: 20850688</identifier><language>eng</language><publisher>Netherlands: Elsevier Ltd</publisher><subject>Allergy and Immunology ; Animals ; Antibodies, Bacterial - blood ; Brucella abortus ; Brucella abortus - classification ; Brucella Vaccine - immunology ; Brucellosis ; Brucellosis, Bovine - diagnosis ; Brucellosis, Bovine - immunology ; Brucellosis, Bovine - prevention & control ; Cattle ; Enzyme-Linked Immunosorbent Assay - methods ; Enzyme-Linked Immunosorbent Assay - veterinary ; Enzymes ; Research Report ; Sensitivity and Specificity ; Sheep ; Vaccines</subject><ispartof>Vaccine, 2010-10, Vol.28 (S5), p.F49-F53</ispartof><rights>2010</rights><rights>Copyright © 2010. Published by Elsevier Ltd.</rights><rights>Copyright Elsevier Limited Oct 1, 2010</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c427t-4397e4402300d847a197565708bb4b859cbff6e140446f3d374dc1c8620aad783</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1497227759?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995,64385,64387,64389,72469</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20850688$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wolfram, J.H</creatorcontrib><creatorcontrib>Kokanov, S.K</creatorcontrib><creatorcontrib>Verkhovsky, O.A</creatorcontrib><title>Diagnostic and Vaccine Chapter</title><title>Vaccine</title><addtitle>Vaccine</addtitle><description>Abstract The first report in this chapter describes the development of a killed composite vaccine. 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The results indicated that the competitive enzyme-linked immunosorbent assay is more sensitive than traditional tests for detecting antibodies to Brucella abortus in naturally and experimentally infected cattle.</description><subject>Allergy and Immunology</subject><subject>Animals</subject><subject>Antibodies, Bacterial - blood</subject><subject>Brucella abortus</subject><subject>Brucella abortus - classification</subject><subject>Brucella Vaccine - immunology</subject><subject>Brucellosis</subject><subject>Brucellosis, Bovine - diagnosis</subject><subject>Brucellosis, Bovine - immunology</subject><subject>Brucellosis, Bovine - prevention & control</subject><subject>Cattle</subject><subject>Enzyme-Linked Immunosorbent Assay - methods</subject><subject>Enzyme-Linked Immunosorbent Assay - veterinary</subject><subject>Enzymes</subject><subject>Research Report</subject><subject>Sensitivity and Specificity</subject><subject>Sheep</subject><subject>Vaccines</subject><issn>0264-410X</issn><issn>1873-2518</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkU1rGzEQhkVpqR23P6HG0ENP64y-tZeE4nyCoYekxTeh1c42cta7jrQO5N9nF7sN5OKTQDzzDvO8hHyjMKdA1el6_uy8Dw3OGfR_IOYg6QcypkbzjElqPpIxMCUyQWE1IicprQFAcpp_JiMGRoIyZkymF8H9bdrUBT9zTTn7sw-dLR7ctsP4hXyqXJ3w6-GdkN9Xl_eLm2z56_p28XOZecF0lwmeaxQCGAcojdCO5loqqcEUhSiMzH1RVQqpACFUxUuuRempN4qBc6U2fEJ-7HO3sX3aYersJiSPde0abHfJGpUPaYwfJfu9HLTieU9-f0eu211s-jMsFblmTGs5UHJP-dimFLGy2xg2Lr5YCnYwbdf2YNoOpi0I25vu56aH9F2xwfL_1D-1PXC-B7D39hww2uQDNh7LENF3tmzD0RVn7xJ8HZrgXf2IL5jerrGJWbB3Q91D23QoWssVfwU-QqJc</recordid><startdate>20101001</startdate><enddate>20101001</enddate><creator>Wolfram, J.H</creator><creator>Kokanov, S.K</creator><creator>Verkhovsky, O.A</creator><general>Elsevier Ltd</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7QL</scope><scope>7RV</scope><scope>7T2</scope><scope>7T5</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88C</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>C1K</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>LK8</scope><scope>M0R</scope><scope>M0S</scope><scope>M0T</scope><scope>M1P</scope><scope>M2O</scope><scope>M7N</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20101001</creationdate><title>Diagnostic and Vaccine Chapter</title><author>Wolfram, J.H ; Kokanov, S.K ; Verkhovsky, O.A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c427t-4397e4402300d847a197565708bb4b859cbff6e140446f3d374dc1c8620aad783</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Allergy and Immunology</topic><topic>Animals</topic><topic>Antibodies, Bacterial - blood</topic><topic>Brucella abortus</topic><topic>Brucella abortus - classification</topic><topic>Brucella Vaccine - immunology</topic><topic>Brucellosis</topic><topic>Brucellosis, Bovine - diagnosis</topic><topic>Brucellosis, Bovine - immunology</topic><topic>Brucellosis, Bovine - prevention & control</topic><topic>Cattle</topic><topic>Enzyme-Linked Immunosorbent Assay - methods</topic><topic>Enzyme-Linked Immunosorbent Assay - veterinary</topic><topic>Enzymes</topic><topic>Research Report</topic><topic>Sensitivity and Specificity</topic><topic>Sheep</topic><topic>Vaccines</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wolfram, J.H</creatorcontrib><creatorcontrib>Kokanov, S.K</creatorcontrib><creatorcontrib>Verkhovsky, O.A</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Nursing & Allied Health Database</collection><collection>Health and Safety Science Abstracts (Full archive)</collection><collection>Immunology Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Healthcare Administration Database (Alumni)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Research Library</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Vaccine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wolfram, J.H</au><au>Kokanov, S.K</au><au>Verkhovsky, O.A</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Diagnostic and Vaccine Chapter</atitle><jtitle>Vaccine</jtitle><addtitle>Vaccine</addtitle><date>2010-10-01</date><risdate>2010</risdate><volume>28</volume><issue>S5</issue><spage>F49</spage><epage>F53</epage><pages>F49-F53</pages><issn>0264-410X</issn><eissn>1873-2518</eissn><abstract>Abstract The first report in this chapter describes the development of a killed composite vaccine. This killed vaccine is non-infectious to humans, other animals, and the environment. The vaccine has low reactivity, is non-abortive, and does not induce pathomorphological alterations to the organs of vaccinated animals. The second report of this chapter describes the diagnostic value of a competitive enzyme-linked immunosorbent assay for detecting Brucella -specific antibodies and its ability to discriminate vaccinated cattle from infected cattle. The results indicated that the competitive enzyme-linked immunosorbent assay is more sensitive than traditional tests for detecting antibodies to Brucella abortus in naturally and experimentally infected cattle.</abstract><cop>Netherlands</cop><pub>Elsevier Ltd</pub><pmid>20850688</pmid><doi>10.1016/j.vaccine.2010.04.051</doi></addata></record> |
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| subjects | Allergy and Immunology Animals Antibodies, Bacterial - blood Brucella abortus Brucella abortus - classification Brucella Vaccine - immunology Brucellosis Brucellosis, Bovine - diagnosis Brucellosis, Bovine - immunology Brucellosis, Bovine - prevention & control Cattle Enzyme-Linked Immunosorbent Assay - methods Enzyme-Linked Immunosorbent Assay - veterinary Enzymes Research Report Sensitivity and Specificity Sheep Vaccines |
| title | Diagnostic and Vaccine Chapter |
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