Multifunctional Nanoparticles for Dual Imaging

For imaging with different modalities, labels, which provide contrast for all modalities, are required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell offer progress in this direction. Both, the core and the polymer shell, can be synthesized to be fluorescent, magnetic...

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Veröffentlicht in:Analytical chemistry (Washington) 2011-04, Vol.83 (8), p.2877-2882
Hauptverfasser: Ali, Z, Abbasi, A. Z, Zhang, F, Arosio, P, Lascialfari, A, Casula, M. F, Wenk, A, Kreyling, W, Plapper, R, Seidel, M, Niessner, R, Knöll, J, Seubert, A, Parak, W. J
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container_end_page 2882
container_issue 8
container_start_page 2877
container_title Analytical chemistry (Washington)
container_volume 83
creator Ali, Z
Abbasi, A. Z
Zhang, F
Arosio, P
Lascialfari, A
Casula, M. F
Wenk, A
Kreyling, W
Plapper, R
Seidel, M
Niessner, R
Knöll, J
Seubert, A
Parak, W. J
description For imaging with different modalities, labels, which provide contrast for all modalities, are required. Colloidal nanoparticles composed out of an inorganic core and a polymer shell offer progress in this direction. Both, the core and the polymer shell, can be synthesized to be fluorescent, magnetic, or radioactive. When different cores are combined with different polymer shells, different types of particles for dual imaging can be obtained, as for example, fluorescent cores with radioactive polymer shells. Properties and perspectives of such nanoparticles for multimodal imaging are discussed.
doi_str_mv 10.1021/ac103261y
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subjects Analytical chemistry
Chemistry
Colloids - chemical synthesis
Colloids - chemistry
Exact sciences and technology
Fluorescence
Fluorescent Dyes - chemical synthesis
Fluorescent Dyes - chemistry
Magnetics
Molecular Imaging
Nanoparticles
Nanoparticles - chemistry
Polymers
Polymers - chemical synthesis
Polymers - chemistry
Radioactive materials
Spectrometric and optical methods
title Multifunctional Nanoparticles for Dual Imaging
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