Association between focal erosions and generalised bone loss in psoriatic arthritis
All PsA patients (n=2212) PsA patients without erosions (n=889) PsA patients with erosions (n=567) p Value Gender Male 47.6 45.72 51.5 0.03 Female 52.4 54.28 48.5 Age Mean (SD) 43.52 (13.83) 44.95 (14.24) 41.98 (14.24)
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| Veröffentlicht in: | Annals of the rheumatic diseases 2011-07, Vol.70 (7), p.1345-1347 |
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| container_title | Annals of the rheumatic diseases |
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| creator | Anandarajah, A P El-Taha, M Peng, C Reed, G Greenberg, J D Ritchlin, C T |
| description | All PsA patients (n=2212) PsA patients without erosions (n=889) PsA patients with erosions (n=567) p Value Gender Male 47.6 45.72 51.5 0.03 Female 52.4 54.28 48.5 Age Mean (SD) 43.52 (13.83) 44.95 (14.24) 41.98 (14.24) |
| doi_str_mv | 10.1136/ard.2010.148452 |
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[...]we found that PsA patients with erosions had a significantly lower lumbar spine BMD than those without erosions even when adjusted for use of steroids, DMARDs, anti-TNF agents and osteoporosis medications.</description><identifier>ISSN: 0003-4967</identifier><identifier>EISSN: 1468-2060</identifier><identifier>DOI: 10.1136/ard.2010.148452</identifier><identifier>PMID: 21325427</identifier><identifier>CODEN: ARDIAO</identifier><language>eng</language><publisher>London: BMJ Publishing Group Ltd and European League Against Rheumatism</publisher><subject>Adult ; Arthritis, Psoriatic - complications ; Biological and medical sciences ; Bone Density - physiology ; Bone Diseases, Metabolic - etiology ; Dermatology ; Diseases of the osteoarticular system ; Drug dosages ; Female ; Humans ; Inflammatory joint diseases ; Lumbar Vertebrae - physiopathology ; Male ; Medical sciences ; Middle Aged ; Osteoporosis ; Osteoporosis. Osteomalacia. Paget disease ; Psoriasis. Parapsoriasis. Lichen ; Tumor necrosis factor-TNF</subject><ispartof>Annals of the rheumatic diseases, 2011-07, Vol.70 (7), p.1345-1347</ispartof><rights>Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><rights>2015 INIST-CNRS</rights><rights>Copyright: 2011 Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to http://group.bmj.com/group/rights-licensing/permissions</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-b427t-9ee4a89c6be8f6b3fe451620f63df1075631c3b183fc05d0351498e802d411b93</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttp://ard.bmj.com/content/70/7/1345.full.pdf$$EPDF$$P50$$Gbmj$$H</linktopdf><linktohtml>$$Uhttp://ard.bmj.com/content/70/7/1345.full$$EHTML$$P50$$Gbmj$$H</linktohtml><link.rule.ids>114,115,315,782,786,3198,23578,27931,27932,77608,77639</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=24242222$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/21325427$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Anandarajah, A P</creatorcontrib><creatorcontrib>El-Taha, M</creatorcontrib><creatorcontrib>Peng, C</creatorcontrib><creatorcontrib>Reed, G</creatorcontrib><creatorcontrib>Greenberg, J D</creatorcontrib><creatorcontrib>Ritchlin, C T</creatorcontrib><title>Association between focal erosions and generalised bone loss in psoriatic arthritis</title><title>Annals of the rheumatic diseases</title><addtitle>Ann Rheum Dis</addtitle><description>All PsA patients (n=2212) PsA patients without erosions (n=889) PsA patients with erosions (n=567) p Value Gender Male 47.6 45.72 51.5 0.03 Female 52.4 54.28 48.5 Age Mean (SD) 43.52 (13.83) 44.95 (14.24) 41.98 (14.24) <0.01 Median (IQR) 44 (33â[euro]"53) 45 (36â[euro]"54) 41 (32â[euro]"52) Health Assessment Questionnaire Score Mean (SD) 0.51 (0.39) 0.52 (0.39) 0.49 (0.39) 0.09 Median (IQR) 0.38 (0.14â[euro]"0.75) 0.38 (0.25â[euro]"0.75) 0.38 (0.13â[euro]"0.75) Steroid % no use 80.42 79.7 82.83 0.14 % use 19.58 20.3 17.17 Methotrexate % no use 46.16 48.71 45.33 0.21 % use 53.84 51.29 54.67 Other disease-modifying antirheumatic drugs % no use 36.39 39.15 34.89 0.07 % use 63.61 60.85 65.61 Biological agents % no use 43.49 45.56 42.68 0.28 % use 56.51 54.44 57.32 Disease duration, years 9.11 7.49 11.88 <0.01 C reactive protein, mg/dl 2.38 2.13 2.64 0.34 The mean T-score for the lumbar spine for all patients with PsA was -0.33, but the mean T-score was significantly lower in patients in group 2 than in those in group 1 (-0.61 vs -0.11; p<0.01). 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[...]we found that PsA patients with erosions had a significantly lower lumbar spine BMD than those without erosions even when adjusted for use of steroids, DMARDs, anti-TNF agents and osteoporosis medications.</abstract><cop>London</cop><pub>BMJ Publishing Group Ltd and European League Against Rheumatism</pub><pmid>21325427</pmid><doi>10.1136/ard.2010.148452</doi><tpages>3</tpages></addata></record> |
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| ispartof | Annals of the rheumatic diseases, 2011-07, Vol.70 (7), p.1345-1347 |
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| subjects | Adult Arthritis, Psoriatic - complications Biological and medical sciences Bone Density - physiology Bone Diseases, Metabolic - etiology Dermatology Diseases of the osteoarticular system Drug dosages Female Humans Inflammatory joint diseases Lumbar Vertebrae - physiopathology Male Medical sciences Middle Aged Osteoporosis Osteoporosis. Osteomalacia. Paget disease Psoriasis. Parapsoriasis. Lichen Tumor necrosis factor-TNF |
| title | Association between focal erosions and generalised bone loss in psoriatic arthritis |
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